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New type of cell contributes to increased understanding of ALS


Credit: Ulf Sirborn
The causes of the serious muscle disease ALS still remain unknown. Now, researchers at Karolinska Institutet and KTH Royal Institute of Technology, among others, have examined a type of cell in the brain blood vessels that could explain the unpredictable disease origins and dynamics. The results indicate a hitherto unknown connection between the nervous and vascular systems. The study, which is published in
Nature Medicine, has potential implications for earlier diagnoses and future treatments.
ALS (amyotrophic lateral sclerosis) is a neurodegenerative disease of the motor neurons that eventually causes muscular atrophy, paralysis and death. There is currently no cure. ....

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One in ten have long-term effects 8 months following mild COVID-19


Credit: Ludvig Kostyal
Eight months after mild COVID-19, one in ten people still has at least one moderate to severe symptom that is perceived as having a negative impact on their work, social or home life. The most common long-term symptoms are a loss of smell and taste and fatigue. This is according to a study published in the journal
JAMA, conducted by researchers at Danderyd Hospital and Karolinska Institutet in Sweden.
Since spring 2020, researchers at Danderyd Hospital and Karolinska Institutet have conducted the so-called COMMUNITY study, with the main purpose of examining immunity after COVID-19. In the first phase of the study in spring 2020, blood samples were collected from 2,149 employees at Danderyd Hospital, of whom about 19 percent had antibodies against SARS-CoV-2. Blood samples have since then been collected every four months, and study participants have responded to questionnaires regarding long-term symptoms and their impact on the quality of life. ....

United States , Uppsala Lan , Karolinska Institutet , Axel Rosell , Sebastian Havervall , Saram Mangsbo , Peter Nilsson , Mia Phillipson , Leif Lundblad , Jonas Klingstr , Sophia Hober , Jonas Christina , Sara Mangsbo , Uppsala University , Erling Persson Family Foundation , Alice Wallenberg Foundation , Research Letter , Jochnick Foundation , Journal Of The American Medical Association , Atlas Copco , Public Health Agency Of Sweden , Health Care Workers , Danderyd Hospital , Public Health Agency , Professor Mia , Region Stockholm ,