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T-Cypher Bio Announces Formation of Scientific Advisory Board

T-Cypher Bio Announces Formation of Scientific Advisory Board
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United States , United Kingdom , Uciane Scarlett , Thomas Lars Andresen , Graham Ogg Fmedsci , Graham Ogg , Fiona Powriefmedsci , Andrew Mcmichaelfmedsci , Division Of Cancer Medicine , Oxford Sciences Innovation , University Of Texas Md Anderson Cancer Center , University Of Oxford , Kennedy Institute Of Rheumatology , Life Sciences , Academy Medical Sciences , Department Of Solid Tumour Cell Therapy , Cypher Bio Announces Formation , Scientific Advisory , T Cypher Bio , Scientific Advisory Board , Professor Graham Ogg , Academy Medical , Lars Andresen , Interim Executive Chair , Cassian Yee , Solid Tumour Cell Therapy ,

Mestag Therapeutics launches with seed financing of $11 million to develop therapeutics targeting activated fibroblast populations across inflammatory disease and cancer

Published: Apr 21, 2021
- Backed by leading healthcare investors including SV Health Investors -
Cambridge, UK, 20 April 2021 – Mestag Therapeutics (“Mestag”), a breakthrough inflammatory disease and immuno-oncology company, today announced its launch with $11 million seed financing from healthcare investors SV Health Investors and Johnson & Johnson Innovation – JJDC, Inc. (“JJDC”).
The Company’s mission is to develop new medicines for patients by targeting activated fibroblast populations and their role in influencing immune effector cells in disease. Powerful new technologies enable diseased tissues to be analyzed at a single-cell level, and this work has uncovered discrete fibroblast cell sub-populations shared across diseases, acting as “immune sentinels” in perpetuating, and progressing disease. Mestag is building a pipeline of first in class therapeutics to interrupt fibroblast-mediated effects on immune cells in inflammatory disease and im ....

United States , United Kingdom , Mark Coles , Davida Tuveson , Michael Brenner , Soumya Raychaudhuri , Julia Wilson , Sanofi Aventis , Phouman Ashrafian , Susan Hill , Chris Buckley , Michaelb Brenner , David Tuveson , Research Early Development , Sv Health Investors , Kennedy Institute Of Rheumatology , Lustgarten Foundation , Jjdc Inc , Musculoskeletal Sciences , University Of Oxford , Cancer Center , Nuffield Department Of Orthopaedics , Head Of Group Finance At Horizon Discovery , Infrastructure For Birmingham Health Partners , Jw Communications , Research Crescendo Biologics ,

Historic Fife postcards by 19th century artist Reginald Phillimore celebrated by retired consultant rheumatologist

Historic Fife postcards by 19th century artist Reginald Phillimore celebrated by retired consultant rheumatologist
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Michael Alexander speaks to retired consultant rheumatologist Jan Bondeson about his fascination with the works of a 19th century postcard artist who created various images of landmarks in the East Neuk of Fife.
When Swedish-born physician Jan Bondeson retired as a lecturer and consultant rheumatologist at the Cardiff University School of Medicine a few years ago, it gave him more time to indulge in his hobby of collecting books, art and postcards. ....

United Kingdom , Bass Rock , East Lothian , Tantallon Castle , North Berwick , Newark Castle , Scottish Borders , Earlsferry Reginald Phillimore , Phillimore Fife , Jan Bondeson Macduffs , Phillimore Edinburgh , Donald Deaks , Greyfriar Bobby , Reginald Phillimore , Jan Bondeson , Jan Bondeson Reginald Phillimore , London Monster , Jan Bondeson Newark Castle , Lady Janet Anstruther , Queen Victoria , Mary Pearson , William Phillimore , Michael Alexander , Jan Bondeson Kilconquhar Church , Lund University , Kennedy Institute Of Rheumatology ,

Vaccine Responses in Older Adults Boosted by Drug That Helps Immune Cells Self-Clean

Vaccine Responses in Older Adults Boosted by Drug That Helps Immune Cells Self-Clean
December 16, 2020
One needs to look no further than the COVID-19 pandemic to highlight the point that older adults are in the high-risk category for infectious diseases. With vaccines starting to be rolled out in the United States, so too is hope for the protection of this vulnerable group. While most vaccines are less efficacious in older adults, little is known about the molecular mechanisms that underpin this.
A new study shows that autophagy, a process critical for the maintenance of immune memory in mice, is specifically induced in vaccine-induced antigen-specific CD8+ T cells in healthy human volunteers. In addition, a drug that boosts the removal of cellular debris in immune cells, spermidine, may increase the protective effects of vaccines in older adults. The results may lead to new approaches to protect older individuals from viruses such as the one causing the current COVID- ....

United States , Anna Katharina Simon , Ghada Alsaleh , University Of Oxford , Kennedy Institute Of Rheumatology , Kennedy Institute , ஒன்றுபட்டது மாநிலங்களில் , அண்ணா காதரின சிமோன் , பல்கலைக்கழகம் ஆஃப் ஆக்ஸ்ஃபர்ட் , கெந்நெடீ நிறுவனம் ஆஃப் வாத நோய் , கெந்நெடீ நிறுவனம் ,

Drug may boost vaccine responses in older adults

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A drug that boosts the removal of cellular debris in immune cells may increase the protective effects of vaccines in older adults, a study published today in
eLife shows.
The results may lead to new approaches to protect older individuals from viruses such as the one causing the current COVID-19 pandemic and influenza.
Older adults are at high risk of being severely affected by infectious diseases, but unfortunately most vaccines in this age group are less efficient than in younger adults, explains lead author Ghada Alsaleh, a postdoctoral researcher at the Kennedy Institute of Rheumatology, University of Oxford, UK. ....

United Kingdom , Josie Eade , Emily Packer , Ghada Alsaleh , Anna Katharina Simon , University Of Oxford , Alice Wallenberg Foundation , Kennedy Institute Of Rheumatology , Nuffield Department Of Orthopaedics , Musculoskeletal Sciences , Max Planck Society , Howard Hughes Medical Institute , Kennedy Institute , Media Relations Manager , Acting Communications Manager , ஒன்றுபட்டது கிஂக்டம் , ஜோசி எாடெ , எமிலி ப்யாகர் , அண்ணா காதரின சிமோன் , பல்கலைக்கழகம் ஆஃப் ஆக்ஸ்ஃபர்ட் , ஆலிஸ் வாலன்பெர்க் அடித்தளம் , கெந்நெடீ நிறுவனம் ஆஃப் வாத நோய் , நுஃபையீல்ட் துறை ஆஃப் எலும்பியல் , தசைக்கூட்டு அறிவியல் , ஹோவர்ட் ஹக்ஸ் மருத்துவ நிறுவனம் , கெந்நெடீ நிறுவனம் ,