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New research studies to help diagnose and treat Long COVID funded by NIHR


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People experiencing Long COVID will benefit from a comprehensive package of new NIHR-funded research to help improve understanding of the condition, from diagnosis and treatment through to rehabilitation and recovery. 15 projects from across the UK have been awarded a total of £19.6 million to examine causes of Long COVID, trial drugs to tackle it, and investigate symptoms such as breathlessness and ‘brain fog’ that have become synonymous with the condition. Studies will also evaluate health services, such as Long COVID clinics, and explore ways patients can monitor the condition to optimise their recovery and return to work.
Health and Social Care Secretary, Sajid Javid, said, ‘Long COVID can have serious and debilitating long-term effects for thousands of people across the UK, which can make daily life extremely challenging. This new research is absolutely essential to improve diagnosis and treatments and will be life-changing for those who are battling lon ....

United Kingdom , Sajid Javid , Daniel Prieto Alhambra , Musculoskeletal Sciences , Professor Fergus Gleeson At Oxford University , Oxford Biomedical Research Centre , Nuffield Department Of Primary Care Health Sciences , Nuffield Department Of Orthopaedics , University Of Sheffield , Social Care Secretary , Professor Fergus Gleeson , Oxford University , Professor Jim Wild , Sue Ziebland , Medical Sociology , Nuffield Department , Primary Care Health Sciences , Performing Medicine , Professor Daniel Prieto Alhambra , ஒன்றுபட்டது கிஂக்டம் , சஜித் ஜாவிட் , டேனியல் ப்ரீடோ அல்ஹம்ப்ரா , தசைக்கூட்டு அறிவியல் , ஆக்ஸ்ஃபர்ட் உயிர் மருத்துவ ஆராய்ச்சி மையம் , நுஃபையீல்ட் துறை ஆஃப் ப்ரைமரீ பராமரிப்பு ஆரோக்கியம் அறிவியல் , நுஃபையீல்ட் துறை ஆஃப் எலும்பியல் ,

Mestag Therapeutics launches with seed financing of $11 million to develop therapeutics targeting activated fibroblast populations across inflammatory disease and cancer


Published: Apr 21, 2021
- Backed by leading healthcare investors including SV Health Investors -
Cambridge, UK, 20 April 2021 – Mestag Therapeutics (“Mestag”), a breakthrough inflammatory disease and immuno-oncology company, today announced its launch with $11 million seed financing from healthcare investors SV Health Investors and Johnson & Johnson Innovation – JJDC, Inc. (“JJDC”).
The Company’s mission is to develop new medicines for patients by targeting activated fibroblast populations and their role in influencing immune effector cells in disease. Powerful new technologies enable diseased tissues to be analyzed at a single-cell level, and this work has uncovered discrete fibroblast cell sub-populations shared across diseases, acting as “immune sentinels” in perpetuating, and progressing disease. Mestag is building a pipeline of first in class therapeutics to interrupt fibroblast-mediated effects on immune cells in inflammatory disease and im ....

United States , United Kingdom , Mark Coles , Davida Tuveson , Michael Brenner , Soumya Raychaudhuri , Julia Wilson , Sanofi Aventis , Phouman Ashrafian , Susan Hill , Chris Buckley , Michaelb Brenner , David Tuveson , Research Early Development , Sv Health Investors , Kennedy Institute Of Rheumatology , Lustgarten Foundation , Jjdc Inc , Musculoskeletal Sciences , University Of Oxford , Cancer Center , Nuffield Department Of Orthopaedics , Head Of Group Finance At Horizon Discovery , Infrastructure For Birmingham Health Partners , Jw Communications , Research Crescendo Biologics ,

Drug may boost vaccine responses in older adults


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A drug that boosts the removal of cellular debris in immune cells may increase the protective effects of vaccines in older adults, a study published today in
eLife shows.
The results may lead to new approaches to protect older individuals from viruses such as the one causing the current COVID-19 pandemic and influenza.
Older adults are at high risk of being severely affected by infectious diseases, but unfortunately most vaccines in this age group are less efficient than in younger adults, explains lead author Ghada Alsaleh, a postdoctoral researcher at the Kennedy Institute of Rheumatology, University of Oxford, UK. ....

United Kingdom , Josie Eade , Emily Packer , Ghada Alsaleh , Anna Katharina Simon , University Of Oxford , Alice Wallenberg Foundation , Kennedy Institute Of Rheumatology , Nuffield Department Of Orthopaedics , Musculoskeletal Sciences , Max Planck Society , Howard Hughes Medical Institute , Kennedy Institute , Media Relations Manager , Acting Communications Manager , ஒன்றுபட்டது கிஂக்டம் , ஜோசி எாடெ , எமிலி ப்யாகர் , அண்ணா காதரின சிமோன் , பல்கலைக்கழகம் ஆஃப் ஆக்ஸ்ஃபர்ட் , ஆலிஸ் வாலன்பெர்க் அடித்தளம் , கெந்நெடீ நிறுவனம் ஆஃப் வாத நோய் , நுஃபையீல்ட் துறை ஆஃப் எலும்பியல் , தசைக்கூட்டு அறிவியல் , ஹோவர்ட் ஹக்ஸ் மருத்துவ நிறுவனம் , கெந்நெடீ நிறுவனம் ,