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Cryo-EM reveals Key Insight into Vital DNA repair process


Apr 24 2021 Read 4 Times
Scientists at the University of Glasgow have revealed key insights into a vital DNA repair process which is implicated in resistance to cancer treatments, using cryo-electron microscopy.
Led by the University of Glasgow the research(1) is based on data and models collected from the Scottish Centre for Macromolecular Imaging (SCMI) and was conducted with colleagues at the University of Dundee.
The study looks at a toxic type of DNA damage called inter-strand crosslinks, which is normally repaired through a process initiated by a single molecule of ubiquitin – a protein commonly found in humans, animals and plants – being attached to each of the affected strands of DNA. In order to complete the DNA repair process the ubiquitin molecule must also be successfully removed from the damaged site – a process known as deubiquitination. ....

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Ada Jesus died due to Nigeria's poor healthcare system- Nigerian Tweeps


Published 21 April 2021
Nigerian Twitter users have taken to the microblogging site to air their opinion about the death of popular comedienne, Ada Jesus. According to the users of the online platform, the comedienne died due to the country’s poor healthcare system.
So far, tweets about the comedienne’s death have generated a lot of engagements on Twitter and it has garnered over 12,000 tweets. The late skit maker trends at number two on the microblogging site.
The comedienne died two days after celebrating her birthday. The young lady had been battling kidney disease and eventually stroke which left her incapacitated before her death. ....

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GM  Brenda Barnette's Decade at LA Animal Services –Transformation or Tyranny?


ANIMAL WATCH-The stern face of a Pit Bull adorns the Best Friends’ Animal Society’s Facebook  announcement, “Together, We Made LA a No-Kill City,” but there is no mention of Los Angeles Animal Services nor General Manager Brenda Barnette as part of this accomplishment.
Was this an oversight? 
Barnette is retiring as General Manager of LAAS after a decade of  brutal attacks by Pit Bulls and other dogs with known-aggressive behavior on innocent and unsuspecting victims adopters, visitors, and employees at Los Angeles City animal shelters. These are dogs Barnette has made available for adoption, often with knowledge of their backgrounds and with written comments/warnings by shelter staff.  ....

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2021 NFL Draft Mailbag: Falcons plans at No. 4, teams that could trade up and more

2021 NFL Draft Mailbag: Falcons plans at No. 4, teams that could trade up and more
si.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from si.com Daily Mail and Mail on Sunday newspapers.

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Man attacks doctor after his 3-yr-old dies in the hospital


Man attacks doctor after his 3-yr-old dies in the hospital
Man attacks doctor after his 3-yr-old dies in the hospital
ByBellie ThomasBellie Thomas / Updated: Mar 13, 2021, 06:00 IST
After the death of a three-year-old boy, who did not respond to
treatment at a private hospital in Hebbal, the child’s father and relatives are alleged to have attacked a 30-year-old pediatrician at the hospital on Monday. The doctor filed a complaint with the
Kodigehalli police who have booked the deceased boy’s father Pradeep Kumar and a relative, Shiv Kumar.
Dr Abhiram Kumar, a
specialist at the Pediatric Intensive Care Unit (PICU) of the Aster ....

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