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Better CNS Control in Children With ALL: 'Goldilocks' Approach

Better CNS Control in Children With ALL: 'Goldilocks' Approach
medscape.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medscape.com Daily Mail and Mail on Sunday newspapers.

Nordrhein Westfalen , United Kingdom , Jingyan Tang , Gabriele Escherich , Christina Halsey , National Natural Science Foundation Of China , National Cancer Institute , Chinese Children Cancer Group , University Of Glasgow , Shanghai Children Medical Center , University Medical Center Hamburg , University Medical Center Hamburg Eppendorf , Chinese Children , Cancer Group , Shanghai Children , National Natural Science Foundation , னோற்ர்ேன் வெஸ்ட்ஃபாலன் , ஒன்றுபட்டது கிஂக்டம் , ஜிங்கியன் டாங் , தேசிய இயற்கை அறிவியல் அடித்தளம் ஆஃப் சீனா , தேசிய புற்றுநோய் நிறுவனம் , சீன குழந்தைகள் புற்றுநோய் குழு , பல்கலைக்கழகம் ஆஃப் கிளாஸ்கோ , ஷாங்காய் குழந்தைகள் மருத்துவ மையம் , பல்கலைக்கழகம் மருத்துவ மையம் ஹாம்பர்க் , சீன குழந்தைகள் ,

International collaboration aims to develop better therapy for childhood acute lymphoblastic leukemia

International collaboration aims to develop better therapy for childhood acute lymphoblastic leukemia
Scientists at St. Jude Children s Research Hospital are working with colleagues in China to develop better therapy for childhood acute lymphoblastic leukemia (ALL). Results from a large phase 3 noninferiority clinical trial definitively showed that vincristine and dexamethasone pulses can be eliminated in patients with low-risk disease. The findings were published today in
The
Lancet Oncology.
Adding the chemotherapy vincristine plus a steroid (originally prednisone, and later dexamethasone) as pulse therapy for childhood ALL has been part of standard care since the 1970s. This is despite their being associated with neuropsychological side effects, neuropathy and other late effects. However, to date studies about the need for prolonged treatment with pulse therapy have been inconclusive. ....

Emily Henderson , Jude Children Research Hospital , Chinese Children Cancer Group , Jude Department Of Oncology , Jude Children , Research Hospital , Ching Hon Pui , Jude Department , Chinese Children , Cancer Group , எமிலி ஹென்டர்சன் , ஜூட் குழந்தைகள் ஆராய்ச்சி மருத்துவமனை , சீன குழந்தைகள் புற்றுநோய் குழு , ஜூட் துறை ஆஃப் புற்றுநோயியல் , ஜூட் குழந்தைகள் , ஆராய்ச்சி மருத்துவமனை , சிங் க .ரவ பு , ஜூட் துறை , சீன குழந்தைகள் , புற்றுநோய் குழு ,

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Scientists atSt. JudeChildren’s Research Hospital are working with colleagues in China to develop better therapy for childhood acute lymphoblastic leukemia (ALL). Results from a large phase 3 noninferiority clinical trial definitively showed that vincristine and dexamethasone pulses can be eliminated in patients with low-risk disease. The findings were published today in
The
Lancet Oncology.
Adding the chemotherapy vincristine plus a steroid (originally prednisone, and later dexamethasone) as pulse therapy for childhood ALL has been part of standard care since the 1970s. This is despite their being associated with neuropsychological side effects, neuropathy and other late effects. However, to date studies about the need for prolonged treatment with pulse therapy have been inconclusive. ....

Hong Kong , Hua Jiang , University Of Hong Kong , Hong Kong General , Hui Jiang , Hui Zhang , Jing Chen , Jingyan Tang , Aiguo Liu , Ju Gao , Yingchi Zhang , Wenyu Yang , Changda Liang , Minghua Yang , Kaili Pan , Runming Jin , Yongjun Fang , Chunfu Li , Yiping Zhu , Lirong Sun , Junj Yang , Jiaoyang Cai , Jie Yu , Xuedong Wu , Xiaowen Zhai , Ningling Wang ,

International collaboration helps refine treatment for childhood leukemia

International collaboration helps refine treatment for childhood leukemia
prnewswire.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from prnewswire.com Daily Mail and Mail on Sunday newspapers.

Hong Kong , Hua Jiang , University Of Hong Kong , Hong Kong General , Hui Jiang , Hui Zhang , Jing Chen , Jingyan Tang , Aiguo Liu , Ju Gao , Yingchi Zhang , Wenyu Yang , Changda Liang , Minghua Yang , Kaili Pan , Runming Jin , Yongjun Fang , Chunfu Li , Yiping Zhu , Lirong Sun , Junj Yang , Jiaoyang Cai , Jie Yu , Xuedong Wu , Xiaowen Zhai , Ningling Wang ,