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Smoking cessation drug shows potential to treat Parkinson's disease in females


Smoking cessation drug shows potential to treat Parkinson s disease in females
Texas A&M University College of Medicine ressearchers have recently discovered that cytisine a smoking cessation drug commonly used in Europe reduces the loss of dopamine neurons in females. These findings provide potential evidence for the use of the drug to treat Parkinson s disease or stop its progression in women.
Sara Zarate and Gauri Pandey, graduate students from the lab of Rahul Srinivasan, assistant professor in the Department of Neuroscience & Experimental Therapeutics, are co-first authors of the research. Their findings are published in the
Journal of Neurochemistry. ....

United States , Sara Zarate , Rahul Srinivasan , Gauri Pandey , Emily Henderson , Texasam University College Of Medicine , Department Of Neuroscience Experimental Therapeutics , Experimental Therapeutics , Assistant Professor , Smoking Cessation , Neurodegenerative Disorder , Parkinson 39s Disease , ஒன்றுபட்டது மாநிலங்களில் , சாரா ஜாரதே , ராகுல் ஸ்ரீநிவாசன் , கௌரி பாண்டே , எமிலி ஹென்டர்சன் , துறை ஆஃப் நரம்பியல் சோதனை சிகிச்சை , சோதனை சிகிச்சை , உதவியாளர் ப்ரொஃபெஸர் , புகைத்தல் சிஇஎஸ்எஸ்ஏடிஐஓஎன் ,

Scientists seek to enhance artificial intelligence by integrating brain cells


Scientists seek to enhance artificial intelligence by integrating brain cells
With a new grant from the U.S. Army, a team of scientists will seek to enhance artificial intelligence by integrating brain cells called astrocytes.
By encoding a feature of biological intelligence called reinforcement learning, in which we iteratively learn from successes and failures, deep neural networks (DNNs) have revolutionized artificial intelligence with spectacular demonstrations of mastery in Chess and Go.
But they struggle to deal with the real-world problems encountered daily by humans and other animals. A new collaboration based at MIT posits that a fundamental shortcoming of deep neural networks is that they are merely neural. ....

Ann Graybiel , John Odoherty , Alexander Rakhlin , Mriganka Sur , Pulkit Agrawal , Emily Henderson , Multidiscipinary University Research Initiative , California Institute Of Technology , Us Army , University Of Minnesota , Cognitive Sciences , Picower Institute For , Institute Professor , Newton Professor , Picower Institute , Electrical Engineering , Computer Science , California Institute , Alfonoso Araque , Artificial Intelligence , Brain Cell , மிரகங்க சூர் , எமிலி ஹென்டர்சன் , கலிஃபோர்னியா நிறுவனம் ஆஃப் தொழில்நுட்பம் , எங்களுக்கு இராணுவம் , பல்கலைக்கழகம் ஆஃப் மினசோட்டா ,

Discovery offers a precise route to treat inflammation associated with neuropathic pain


Discovery offers a precise route to treat inflammation associated with neuropathic pain
One of the hallmarks of chronic pain is inflammation, and scientists at the UNC School of Medicine have discovered that anti-inflammatory cells called MRC1
+ macrophages are dysfunctional in an animal model of neuropathic pain. Returning these cells to their normal state could offer a route to treating debilitating pain caused by nerve damage or a malfunctioning nervous system.
The researchers, who published their work in
Neuron, found that stimulating the expression of an anti-inflammatory protein called CD163 reduced signs of neuroinflammation in the spinal cord of mice with neuropathic pain. ....

Jesse Niehaus , Mark Zylka , Emily Henderson , Centers For Disease , School Of Medicine , Neuroscience Center , University Of North Carolina School Medicine , Study Senior Author , North Carolina School , Kenan Distinguished Professor , Cell Biology , Disease Control , Chronic Pain , Animal Model , Anti Inflammatory , Nervous System , Neuropathic Pain , ஜெஸ்ஸி னீேோச் , எமிலி ஹென்டர்சன் , மையங்கள் க்கு நோய் , பள்ளி ஆஃப் மருந்து , நரம்பியல் மையம் , பல்கலைக்கழகம் ஆஃப் வடக்கு கரோலினா பள்ளி மருந்து , படிப்பு மூத்தவர் நூலாசிரியர் , வடக்கு கரோலினா பள்ளி , கெணான் புகழ்பெற்ற ப்ரொஃபெஸர் ,

New molecular driver of frontal circuit maturation discovered


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IMAGE: Hirofumi Morishita, MD, PhD, Associate Professor of Psychiatry, Neuroscience and Opthalmology at the Icahn School of Medicine at Mount Sinai and lead author of the study.
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Credit: Mount Sinai Health System
Mount Sinai Researchers find a new way to prevent attention deficits associated with Fragile X, a leading genetic cause of autism, in an animal model
Corresponding Author: Hirofumi Morishita, MD, PhD, Department of Psychiatry, Neuroscience, Friedman Brain Institute, Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York.
Bottom Line: The adolescent maturation of the frontal cortex is important for establishing cognitive function, and disruption of this process is associated with neurodevelopmental disorders. This study uncovered a new molecular driver of frontal circuit maturation that is essential for cognitive function, and demonstrated, in an animal model, that this mechanis ....

New York , United States , Hirofumi Morishita , Elizabeth Dowling , Why The Research Is Interesting , Icahn School Of Medicine At Mount Sinai , Public Affairs , Development Institute , Mindich Child Health , Friedman Brain Institute , Department Of Psychiatry , Mount Sinai Researchers , Icahn School , Mount Sinai , Research Is Interesting , Medicine Health , Social Behavioral Science , Memory Cognitive Processes , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , ஹிரோபூமி மோரிஷிதா , எலிசபெத் டௌலிஂக் , ஏன் தி ஆராய்ச்சி இருக்கிறது சுவாரஸ்யமானது , இக்ஹ்ன் பள்ளி ஆஃப் மருந்து இல் ஏற்ற சினை , பொது வாழ்க்கைத்தொழில்கள் , வளர்ச்சி நிறுவனம் ,