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Red light put moths in the mood

Study show for the first time that dim red light activates olfactory gene pathways in the antennae of a model species, the yellow peach moth, increasing the sensitivity of males to female sex pheromones, and ultimately promoting reproductive behavior ....

Wei Xiao , Southwest University , Developmental Reproductive Biology , Olfactory Taste , வெய் கிஷியஓ , தென்மேற்கு பல்கலைக்கழகம் , வளர்ச்சி இனப்பெருக்கம் உயிரியல் ,

David Kaplan elected to National Academy of Engineering

Credit: Alonso Nichols
David Kaplan, the Stern Family Professor of Engineering, a Distinguished Professor, and chair of the Department of Biomedical Engineering, has been elected to the National Academy of Engineering in recognition of his contributions to silk-based materials for tissue engineering and regenerative medicine. Election to the National Academies is one of the foremost professional recognitions available to engineers, scientists, and medical experts.
On behalf of my past and current students and colleagues here at Tufts, it is an honor to be recognized by the National Academy of Engineering, said Kaplan.
Kaplan s lab is leading efforts in applying tissue engineering to cellular agriculture (i.e. cell grown meat), the development of 3D brain-like environments in the lab to study neurological diseases and treatments, and the regeneration of tissues, organs and limbs. He is also pioneering methods to manufacture biocompatible medical devices from silk. ....

United States , David Kaplan , Tissue Engineering Resource Center , National Institutes Of Health , Tufts School Of Medicine , Department Of Biomedical Engineering , Tufts School Of Dental Medicine , Columbia University , National Academy Of Engineering , Department Of Chemistry , Initiative For Neural Science , Gordon Research Conference , National Academies , Department Of Chemical , Stern Family Professor , Distinguished Professor , Biomedical Engineering , National Academy , Neural Science , National Institutes , Engineering Resource Center , Tufts School , Dental Medicine , Nature Biotechnology , American Institute , Biological Engineering ,

'Miracle poison' for novel therapeutics

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IMAGE: Liu and his lab engineered botulinum toxin to target new proteins, a critical advance that could lead to new treatments for a range of maladies, including nerve and brain damage,.
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Credit: Casey Atkins Photography, courtesy of Broad Institute
When people hear botulinum toxin, they often think one of two things: a cosmetic that makes frown lines disappear or a deadly poison.
But the miracle poison, as it s also known, has been approved by the F.D.A. to treat a suite of maladies like chronic migraines, uncontrolled blinking, and certain muscle spasms. And now, a team of researchers from Harvard University and the Broad Institute have, for the first time, proved they could rapidly evolve the toxin in the laboratory to target a variety of different proteins, creating a suite of bespoke, super-selective proteins called proteases with the potential to aid in neuroregeneration, regulate growth hormones, calm rampant inflammation, o ....

Travis Blum , David Liu , Michael Packer , Broad Institute , Department Of Chemistry , Harvard University , Harvard Medical School , Howard Hughes Medical Institute Investigator , Centers For Disease Control , Chemical Biology , Min Dong , Thomas Dudley Cabot Professor , Natural Sciences , Disease Control , Biomedical Environmental Chemical Engineering , Cell Biology , Chemistry Physics Materials Sciences , Pharmaceutical Sciences , Medicine Health , Pharmaceutical Science , டிராவிஸ் ப்ளம் , டேவிட் லியூ , மைக்கேல் ப்யாகர் , பரந்த நிறுவனம் , துறை ஆஃப் வேதியியல் , ஹார்வர்ட் பல்கலைக்கழகம் ,

Basic cell health systems wear down in Huntington's disease, novel analysis shows

A new computational approach for analyzing complex datasets shows that as disease progresses, neurons and astrocytes lose the ability to maintain homeostasis. The Geomic approach can be applied to other diseases, authors say. ....

Myriam Heiman , Mary Wertz , Christian Neri , Barbara Gris , Thomas Vogt , Jasmin Cevost , Lucile Megret , Jeff Aaronson , Satish Nair , Jim Rosinski , William Yang , Hilary Wilkinson , Broad Institute , Department Of Brain , National Institutes Of Health , Cognitive Sciences , Picower Institute For , Sorbonne Centre National De La Recherche Scientifique , Sorbonne Universit , Associate Professor , Picower Institute , Centre National De La Recherche Scientifique , National Institutes , Molecular Biology , Mathematics Statistics , Medicine Health ,

Researchers identify a neural pathway critical to correcting behavioral errors

Researchers identify a neural pathway critical to correcting behavioral errors
Mount Sinai researchers have identified a neural pathway through which the brain detects errors and guides subsequent behavioral improvement. This process, called cognitive control, is frequently dysregulated in a wide range of psychiatric disorders.
The team s research, published February 19 in
Neuron, also suggests that neurostimulation of this brain pathway could provide an important mechanism for attention adjustments following behavioral errors.
When errors are committed, such as missing a stop sign or running a red light while driving, it s important for our survival to immediately adapt behavior by paying more attention to prevent further errors. This ability to adapt behavior after erroneous actions are one of the key components of human cognitive control. ....

Kevin Norman , Hirofumi Morishita , Emily Henderson , Icahn School Of Medicine At Mount Sinai , Development Institute , Mindich Child Health , Friedman Brain Institute , Associate Professor , Icahn School , Mount Sinai , Study Senior Author , Faculty Member , கெவின் நார்மன் , ஹிரோபூமி மோரிஷிதா , எமிலி ஹென்டர்சன் , இக்ஹ்ன் பள்ளி ஆஃப் மருந்து இல் ஏற்ற சினை , வளர்ச்சி நிறுவனம் , ப்ரைட்மேன் மூளை நிறுவனம் , இணை ப்ரொஃபெஸர் , இக்ஹ்ன் பள்ளி , ஏற்ற சினை , படிப்பு மூத்தவர் நூலாசிரியர் , ஆசிரிய உறுப்பினர் , மன இறுக்கம் , மனநல மருத்துவம் ,