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Scientists identify new compound that reverses ALS neuron damage

Northwestern University scientists have identified the first compound that eliminates the ongoing degeneration of upper motor neurons that become diseased and are a key contributor to ALS (amyotrophic lateral sclerosis), a swift and fatal neurodegenerative disease that paralyzes its victims. ....

Hande Ozdinler , Patrickg Ryan , Richardb Silverman , Emily Henderson , Northwestern University , Northwestern University Feinberg School Of Medicine , Northwestern University Feinberg School , Translational Medicine , Aon Professor , Amyotrophic Lateral Sclerosis , Clinical Trial , Hereditary Spastic Paraplegia , Motor Neuron Diseases , Motor Neurons , Neurodegenerative Disease , Primary Lateral Sclerosis , எமிலி ஹென்டர்சன் , வடமேற்கு பல்கலைக்கழகம் , வடமேற்கு பல்கலைக்கழகம் ஃபைன்பெர்க் பள்ளி ஆஃப் மருந்து , வடமேற்கு பல்கலைக்கழகம் ஃபைன்பெர்க் பள்ளி , மொழிபெயர்ப்பு மருந்து , ஏயான் ப்ரொஃபெஸர் , மருத்துவ சோதனை , பரம்பரை ஸ்பாஸ்டிக் பரப்பிலேகிய , மோட்டார் நரம்பியல் நோய்கள் , ப்ரைமரீ பக்கவாட்டு ஸ்க்லரோசிஸ் ,

Targeted delivery of highly toxic anti-cancer drug to brain tumors

University of Houston biomedical researcher Sheeren Majd is reporting the development and testing of a new nano-carrier as a potential treatment to deliver highly toxic medicine to glioblastomas, the most common and aggressive form of primary brain tumors. ....

Sheereen Majd , University Of Houston , Advanced Healthcare Materials , Biomedical Environmental Chemical Engineering , Medicine Health , Technology Engineering Computer Science , Nanotechnology Micromachines , பல்கலைக்கழகம் ஆஃப் ஹூஸ்டன் , உயிர் மருத்துவ சுற்றுச்சூழல் இரசாயன பொறியியல் , மருந்து ஆரோக்கியம் , தொழில்நுட்பம் பொறியியல் கணினி அறிவியல் , உயிரி தொழில்நுட்பவியல் ,

Neural pathway critical to correcting behavioral errors related to psych disorders found

Credit: Mount Sinai Health System
Mount Sinai researchers have identified a neural pathway through which the brain detects errors and guides subsequent behavioral improvement. This process, called cognitive control, is frequently dysregulated in a wide range of psychiatric disorders. The team s research, published February 19 in
Neuron, also suggests that neurostimulation of this brain pathway could provide an important mechanism for attention adjustments following behavioral errors.
When errors are committed, such as missing a stop sign or running a red light while driving, it s important for our survival to immediately adapt behavior by paying more attention to prevent further errors. This ability to adapt behavior after erroneous actions is one of the key components of human cognitive control. ....

New York , United States , Long Island , Kevin Norman , Hirofumi Morishita , Health System , Development Institute , Mindich Child Health , Icahn School Of Medicine At Mount Sinai , Friedman Brain Institute , Mount Sinai Health System , Icahn School Of Medicine , Mount Sinai , Associate Professor , Icahn School , Mount Sinai Health , New York City , Mount Sinai Hospital , World Report , Medical Schools , Sinai Health System , Medicine Health , Mental Health , Memory Cognitive Processes , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் ,

Politics and the brain: Attention perks up when politicians break with party lines

Building upon previous work studying the brain and politics, Ingrid Haas, associate professor of political science affiliated with Nebraska s Center for Brain, Biology and Behavior, examined the insula and anterior cingular cortex in 58 individuals using functional Magnetic Resonance Imaging and learned that the human brain processes politically incongruent statements differently. ....

United States , Melissa Baker , Ingrid Haas , Frank Gonzalez , University Of California , University Of Nebraska , Nebraska Center , University Of Arizona , Magnetic Resonance Imaging , Brain Biology , Social Behavioral Science , Political Science , ஒன்றுபட்டது மாநிலங்களில் , மெலிசா ரொட்டி சுடுபவர் , இஂக்ரிட் ஹாஸ் , வெளிப்படையான கோன்சலஸ் , பல்கலைக்கழகம் ஆஃப் கலிஃபோர்னியா , பல்கலைக்கழகம் ஆஃப் நெப்ராஸ்கா , நெப்ராஸ்கா மையம் , பல்கலைக்கழகம் ஆஃப் அரிசோனா , காந்த அதிர்வு இமேஜிங் , மூளை உயிரியல் , சமூக நடத்தை அறிவியல் , பொலிடிகல் அறிவியல் ,

Study Shows Voluntary Running Reduces Neuromuscular Decline In Aging Mice

Date Time
Study Shows Voluntary Running Reduces Neuromuscular Decline In Aging Mice
Their study, published online in Neurobiology of Aging,investigated aging rodents that underwent voluntary running exercise between the ages of 22 and 27 months, which represents roughly 55 to 80 years of age in humans.
“These experiments showed that running significantly improved the neuromuscular decline in mice that underwent running compared to sedentary mice. Our findings support the mantra of ‘use it or lose it’ in regards to the connection between the nervous system and muscles, namely the neuromuscular junction,” said senior author Dr. W. David Arnold, neuromuscular specialist and associate professor at Ohio State Wexner Medical Center. ....

United States , Ohio University , Lou Gehrig , Brian Clark , W David Arnold , Deepti Chugh , National Institutes Of Health , Ohio State Department Of Neurology , Ohio Musculoskeletal Neurological Institute At University , Ohio State University Wexner Medical Center , Ohio State Wexner Medical Center , Neuromuscular Division , College Of Medicine , Ohio State Wexner Medical , Amyotrophic Lateral Sclerosis , Ohio Musculoskeletal , Neurological Institute , Nationwide Children , Ohio State , Biological Chemistry , Physical Medicine , National Institutes , Ohio State University , Physical Activity , Nervous System , Older Adults ,