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Five herbal medicines show potent activity against Babesia duncani in the lab Bay Area Lyme Foundation, a leading sponsor of Lyme disease research in the U.S., today announced the publication of new data finding that five herbal medicines had potent activity compared to commonly-used antibiotics in test tubes against Babesia duncani, a malaria-like parasite found on the West Coast of the U.S. that causes the disease babesiosis. Published in the journal Frontiers in Cellular and Infection Microbiology, the laboratory study was funded in part by the Bay Area Lyme Foundation. Collaborating researchers were from Johns Hopkins Bloomberg School of Public Health, California Center for Functional Medicine, and FOCUS Health Group, Naturopathic. ....
Critical mechanism allows deadly bacteria to gain resistance to antibiotics Researchers have identified a critical mechanism that allows deadly bacteria to gain resistance to antibiotics. The findings offer a potential new drug target in the search for effective new antibiotics as we face the growing threat of antimicrobial resistance (AMR) and infections caused by bacterial pathogens. The study investigated quinolone antibiotics which are used to treat a range of bacterial infections, including TB (tuberculosis). Quinolones work by inhibiting bacterial enzymes, gyrase and topoisomerase IV, thereby preventing DNA replication and RNA synthesis essential to growth. They are highly-successful antimicrobial agents widely used in current medicine, however bacterial resistance to them and other treatments is a serious problem. ....
Study demonstrates the impact of reverse antibiotic on gram-negative bacteria Scientists from Skoltech and MSU have investigated antibiotic nybomycin that could prove effective against bacteria resistant to other antibiotics. Their research was published in the journal Antimicrobial Agents and Chemotherapy. All bacterial cells contain topoisomerases, an important group of enzymes that help deal with spatial difficulties stemming from bacterial cell division associated with circular DNA replication. Topoisomerases can be of two types, I and II, depending on breaks they produce in DNA (one strand or double strand). Type II often acts as a target for antibiotics, including fluoroquinolones (FQ), a common group of antibiotics that comprises levofloxacin, ciprofloxacin, and others. Unfortunately, bacteria easily acquire resistance to FQs through mutations in topoisomerase-encoding genes. The emergence of resistant pathogenic strains is a global problem in healthcare, ....
Healthy lungs produce a natural antibiotic that protects them from infection by routinely killing harmful bacteria on airway surfaces. People with cystic fibrosis, however, are . ....
Study of Over 600,000 Women Shows Almost Half Are Getting The Wrong UTI Treatment 2 MARCH 2021 Across the United States, in both rural and urban settings, most women with private health insurance are receiving inappropriate treatment for their urinary tract infections (UTIs), according to a new study.
Of the 670,450 women included in this research, all of whom had been diagnosed with uncomplicated UTIs between the ages of 18 and 44, nearly half received the wrong antibiotics and over three quarters were prescribed the medicine for too long. (A UTI is declared uncomplicated when the patient has no abnormality or disease that could predispose them to more frequent infections.) ....