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RPT-INSIGHT-Top scientists question the need for COVID-19 booster shots

COVID-19 vaccine developers are making ever bolder assertions that the world will need yearly booster shots, or new vaccines to tackle concerning coronavirus variants, but some scientists question when, or whether, such shots will be needed. ....

South Africa , United States , United Kingdom , White House , District Of Columbia , City Of , San Francisco , South African , Michele Gershberg , Richard Hatchett , Stephane Bancel , Albert Bourla , William Gruber , Anthony Fauci , Julie Steenhuysen , Stephen Hoge , Monica Gandhi , Rajeev Venkayya , Tom Frieden , Kate Kelland , Kate Obrien , University Of California , Us Centers For Disease , Department Of Immunization , Astrazeneca Plc , Coalition For Epidemic Preparedness Innovations ,

Explainer - Who decides if the world needs COVID-19 booster shots?

4 Min Read
(Reuters) - Vaccine makers Moderna Inc and Pfizer Inc, with its German partner BioNTech, have been vocal in their view that the world will soon need COVID-19 booster shots to maintain high levels of immunity. What is less clear, however, is who should make that decision - and based on what evidence.
FILE PHOTO: Vials labelled AstraZeneca, Pfizer - Biontech, Johnson&Johnson, Sputnik V coronavirus disease (COVID-19) vaccine are seen in this illustration picture taken May 2, 2021. REUTERS/Dado Ruvic/Illustration/File Photo
THE MODEL FOR FLU VACCINES
Public health officials have a well-coordinated mechanism, first established in 1952, for determining when seasonal flu vaccines should be updated to cope with fast-mutating strains of influenza. ....

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WHO reviewing Vietnam proposal to produce mRNA COVID-19 vaccines

2 Min Read
FILE PHOTO: A woman receives a vaccine as Vietnam starts its official rollout of AstraZeneca s coronavirus disease (COVID-19) vaccine for health workers, at Hai Duong Hospital for Tropical Diseases, Hai Duong province, Vietnam, March 8, 2021. REUTERS/Thanh Hue/File Photo
HANOI (Reuters) - The World Health Organization (WHO) said on Wednesday it was reviewing a proposal by an unidentified vaccine manufacturer in Vietnam to become an mRNA-based COVID-19 vaccine technology hub in the Southeast Asian country.
MRNA vaccines, like that developed jointly by BionTech and Pfizer, prompt the human body to make a protein that is part of the virus, triggering an immune response. ....

Han I , Republic Of , James Pearson , Thomson Reuters Trust Principles , World Health Organization , Southeast Asian , Thomson Reuters Trust , Corona Virus , Asean Countries , Asia Pacific , Health Medicine , Healthcare Trbc Level 1 , Southeast Asia , ஹான் நான் , குடியரசு ஆஃப் , ஜேம்ஸ் பியர்சன் , தாம்சன் ராய்ட்டர்ஸ் நம்பிக்கை ப்ரிந்ஸிபல்ஸ் , உலகம் ஆரோக்கியம் ஆர்கநைஸேஶந் , தென்கிழக்கு ஆசிய , தாம்சன் ராய்ட்டர்ஸ் நம்பிக்கை , கொரோனா வைரஸ் , யாசீன் நாடுகள் , ஆசியா பெஸிஃபிக் , ஆரோக்கியம் மருந்து , தென்கிழக்கு ஆசியா , தடுப்பு மருந்துகள் ,

Trillium unveils CD47 clinical research priorities as investors await solid tumor data

Trillium Therapeutics is up against some stiff competition to become a leader in the new class of drugs called CD47, which turn off the “don’t eat me” signal transmitted by cancer cells, but CEO Jan Skvarka believes his biotech’s data will stand for themselves. ....

United Kingdom , United States , Jan Skvarka , Amgen Kyprolis , Bristol Myers Squibb Onureg , Unsplash Jan Skvarka , Gilead Sciences , Trillium Therapeutics , Bristol Myers Squibb , Arch Oncology , Forty Seven , Big Pharma , Roche Backed Arch Oncology , Shattuck Labs , Trillium Therapeutics , Immuno Oncology , Drug Development , Clinical Research , Solid Tumor , ஒன்றுபட்டது கிஂக்டம் , ஒன்றுபட்டது மாநிலங்களில் , கிலியட் அறிவியல் , டிரில்லியம் சிகிச்சை , பிரிஸ்டல் மைஸ் ஸ்க்விப்ப் , வளைவு புற்றுநோயியல் , நாற்பது ஏழு ,

Sanofi starts off 'pipeline-in-a-product' rilzabrutinib in rare skin disease, but eyes bigger prize

Apr 23, 2021 10:00am
Sanofi picked up the BTK inhibitor rilzabrutinib in the $3.7 billion acquisition of Principia Biopharma in 2020, a unit now known as Principia Sanofi.
Sanofi has big dreams for rilzabrutinib in diseases ranging from atopic dermatitis to asthma, but up first for the potential blockbuster is a phase 2 read out for the rare skin disease pemphigus vulgaris.
Rilzabrutinib was found to reduce steroid use and improve the quality of life in patients with the disorder, which can cause painful skin blisters and infections, in a midstage clinical trial called Believe. Sanofi presented the data during a late-breaking abstract at the American Academy of Dermatology (AAD) meeting April 23. The drug managed to reduce the severity of lesions at the 12 week and 24 week mark and led to a reduction in steroid use at 12 weeks. ....

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