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Researchers develop comprehensive framework to classify small-cell lung cancer

Researchers from The University of Texas MD Anderson Cancer Center have developed the first comprehensive framework to classify small-cell lung cancer (SCLC) into four unique subtypes, based on gene expression, and have identified potential therapeutic targets for each type in a study published today in Cancer Cell. ....

United States , Lauren Averett Byers , Emily Henderson , University Of Texas Md Anderson Cancer Center , Cancer Center , Neck Medical Oncology , Study Lead Author , Assistant Professor , Lung Cancer , Gene Expression , Non Small Cell Lung Cancer , Small Cell Lung Cancer , ஒன்றுபட்டது மாநிலங்களில் , லாரன் அவேரெட்ட பைர்கள் , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் டெக்சாஸ் ம்ட் ஆண்டர்சன் புற்றுநோய் மையம் , புற்றுநோய் மையம் , கழுத்து மருத்துவ புற்றுநோயியல் , படிப்பு வழி நடத்து நூலாசிரியர் , உதவியாளர் ப்ரொஃபெஸர் , நுரையீரல் புற்றுநோய் , கீந் வெளிப்பாடு , நோயெதிர்ப்பு சிகிச்சை , அல்லாத சிறிய செல் நுரையீரல் புற்றுநோய் , சிறிய செல் நுரையீரல் புற்றுநோய் ,

Study finds genetic clues to pneumonia risk and COVID-19 disparities


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IMAGE: Researchers at Vanderbilt University Medical Center and colleagues have identified genetic factors that increase the risk for developing pneumonia and its severe, life-threatening consequences.
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Credit: Vanderbilt University Medical Center
Researchers at Vanderbilt University Medical Center and colleagues have identified genetic factors that increase the risk for developing pneumonia and its severe, life-threatening consequences.
Their findings, published recently in the
American Journal of Human Genetics, may aid efforts to identify patients with COVID-19 at greatest risk for pneumonia, and enable earlier interventions to prevent severe illness and death.
Despite the increasing availability of COVID-19 vaccines, it will take months to inoculate enough people to bring the pandemic under control, experts predict. In the meantime, thousands of Americans are hospitalized and die from COVID-19 each day. ....

United States , New York , Julie Bastarache , Lisa Bastarache , Hsin Chen , Nancy Cox , Hannah Polikowsky , Megan Shuey , Douglas Shaw , Icahn School Of Medicine At Mount Sinai , University Of North Carolina At Chapel Hill , University Of Texas Md Anderson Cancer Center , National Institutes Of Health , Researchers At Vanderbilt University Medical Center , Vanderbilt University Medical Center , American Journal , Human Genetics , North Carolina , Chapel Hill , Cancer Center , Icahn School , Mount Sinai , Hung Hsin Chen , Lauren Petty , National Institutes , ஒன்றுபட்டது மாநிலங்களில் ,

Study defines small-cell lung cancer subtypes and distinct therapeutic vulnerabilities for each type


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IMAGE: Researchers from The University of Texas MD Anderson Cancer Center have developed the first comprehensive framework to classify small-cell lung cancer (SCLC) into four unique subtypes, based on gene expression,.
view more 
Credit: MD Anderson Cancer Center
HOUSTON Researchers from The University of Texas MD Anderson Cancer Center have developed the first comprehensive framework to classify small-cell lung cancer (SCLC) into four unique subtypes, based on gene expression, and have identified potential therapeutic targets for each type in a study published today in
Cancer Cell.
SCLC is known for rapid, aggressive growth and resistance to treatment, which leads to poor outcomes. While recent advances in immunotherapy and targeted therapy have improved survival for non-small cell lung cancer (NSCLC), progress for SCLC has been limited. ....

United States , University Of Texas , Lauren Averett Byers , Md Anderson Cancer Center Lung , Hope Foundation , University Of Texas Md Anderson Cancer Center , Department Of Defense , University Of Texas Southwestern , Hangar Foundation , National Institutes Of Health Cancer Institute , Cancer Prevention Research Institute Of Texas , Rexanna Foundation For Fighting Lung Cancer , Khalifa Bin Zayed Al Nahyan Foundation , Cancer Center , Neck Medical Oncology , Carl Gay , National Institutes , National Cancer Institute , Texas Southwestern , Cancer Prevention , Research Institute , Lung Cancer Moon Shots Program , Abell Hangar Foundation , Andrew Sabin Family Fellowship , Investigator Award , Fighting Lung ,