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Frontiers | No Association Between Statin Use and the Prognosis of Endometrial Cancer in Women With Type 2 Diabetes


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1PEDEGO Research Unit, Medical Research Center Oulu, Department of Obstetrics and Gynecology, Oulu University Hospital and University of Oulu, Oulu, Finland
2Cancer and Translational Medicine Research Unit, Department of Pathology, Oulu University Hospital and University of Oulu, Oulu, Finland
3Department of Obstetrics and Gynecology, Central Finland Central Hospital, Jyväskylä, Finland
4Department of Oncology, University of Helsinki and Helsinki University Comprehensive Cancer Center, Helsinki, Finland
Preclinical studies have suggested statins have antiproliferative and anti-metastatic effects on endometrial cancer cells. Similarly, most previous epidemiological studies have reported a better prognosis of endometrial cancer in patients who used statins. In this study, we explored the role of statins in the prognosis of endometrial cancer in women with type 2 diabetes in a hospital-based cohort. This retrospective cohort consisted of 119 women with type 2 ....

United States , Ch Ungch Ong Namdo , South Korea , Paijanne Tavastia , San Diego , Satakunta Region , Mellersta Osterbotten , Ha Afon , Kjaer Hansen , Van Arsdale , Mc Menamin , Andrew Tompkins , Bokhman Redux , National Supervisory Authority Of Welfare , Oulu University Hospital , Israeli Gynecologic Oncology Group Study Of Statin , University Hospital Of Oulu , Finnish Medical Society Duodecim , Cancer Genome Atlas Research Network , Finnish Government Research Funds , Graphpad Software , Finnish Society Of Internal Medicine , International Federation Of Gynecology , Advisory Board Of The Finnish Diabetes Society , Aatos Erkko Foundation , Ethics Committee Of Oulu University Hospital ,

Everest Medicines Receives Orphan Drug Designation from the Ministry of Food and Drug Safety in South Korea for Sacituzumab Govitecan-Hziy in Metastatic Triple-Negative Breast Cancer


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SHANGHAI, May 5, 2021 /PRNewswire/  Everest Medicines (HKEX 1952.HK), a biopharmaceutical company focused on developing and commercializing transformative pharmaceutical products in Greater China and other parts of Asia, announced today that the Ministry of Food and Drug Safety  (MFDS) in South Korea has granted Orphan Drug Designation (ODD) for sacituzumab govitecan-hziy (SG), an investigational treatment for adult patients with unresectable locally advanced or metastatic triple-negative breast cancer (TNBC) who have received two or more prior systemic therapies, at least one of them for metastatic disease.
We are very pleased that the Ministry of Food and Drug Safety in South Korea has granted Orphan Drug Designation for SG, which we believe has the potential to become a transformative treatment for patients around the world living with metastatic triple-negative breast cancer – a highly aggressive disease with limited trea ....

United States , South Korea , South Korean , Sacituzumab Govitecan Hziy , Kerry Blanchard , Cancer Association , International Agency For Cancer Research , Ministry Of Food , Gilead Sciences Inc , Everest Medicines , Greater China , Drug Safety , Orphan Drug Designation , New Drug Application , Drug Designation , Negative Breast Cancer , International Agency , Cancer Research , Gilead Sciences , Southeast Asian , Standardized Diagnosis , Advanced Breast Cancer , Breast Cancer Expert Committee , National Cancer Control Center , Breast Cancer Professional Committee , Chinese Anti Cancer Association ,