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Researchers develop new method for charting SARS-CoV-2 spike protein glycosylation

Researchers develop new method for charting SARS-CoV-2 spike protein glycosylation
Researchers have developed a novel, simple and affordable method for N-glycan fingerprinting based on enzymatic fluorescent glycan labeling and electrophoresis. This new method may help us understand important changes in glycosylation in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein – something which could inform future therapeutic research.
Advances in genomics, proteomics and mass spectrometry have enabled scientists to identify specific glycans on proteins and their association with diseases. However, these methods are expensive, require highly trained experts to perform and are not easily available.
Researchers Zhengliang L. Wu and James M. Ertelt released the N-glycans present on a glycoprotein and labeled them enzymatically using fluorophore-conjugated sialic acid and fucose, and separated them using gel electrophoresis. The fingerprint of the gly ....

Ramya Dwivedi , Coronavirus Disease Covid 19 , Sars Cov 2 , Spike Protein , Corona Virus , Gel Electrophoresis , Mass Spectrometry , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , ரம்யா டுவிவேடி , ஸ்பைக் ப்ரோடீந் , கொரோனா வைரஸ் , நிறை ஸ்பெக்ட்ரோமெட்ரி , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,

Genomics Market Worth $35.7 Billion by 2024

Genomics Market Worth $35.7 Billion by 2024 ....

United States , Asia Pacific , Aashish Mehra , Agilent Technologies Inc , Roche Ltd , End User Research Institute , Bio Rad Laboratories Inc , Research Newswire , See Campaign , Thermo Fisher Scientific Inc , Illumina Inc , Service Systems Software , Diagnostic Application , Precision Medicine , End User , Research Institute , Genomics Market , Sample Report , North America , Fisher Scientific , Agilent Technologies , Eurofins Scientific , Bio Rad Laboratories , Oxford Nanopore Technologies , United Kingdom , Genome Microarray Market ,

Genomics reveals distinct patterns of emergence of SARS‐CoV‐2 spike variants in Columbus, Ohio

Genomics reveals distinct patterns of emergence of SARS‐CoV‐2 spike variants in Columbus, Ohio
Genomic sequencing of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has facilitated tracking shifts in viral isolates globally.
The emergence of the D614G mutation gave rise to the more transmissible G‐strain of SARS-COV-2. Studies show that this variant has increased cell binding and viral transmission within in vitro models. More distinct SARS‐CoV‐2 strains with additional changes have emerged over the last few months, rapidly spreading in the United Kingdom.
These variants contain many distinct mutations in the spike (S) gene, particularly N501Y. The rapid transmissibility and the sudden changes to the S gene have raised concerns about changes in the pattern of disease and the potential variability in how COVID-19 patients respond to vaccines or antibody therapies. ....

United States , South Africa , United Kingdom , South African , Susha Cheriyedath , Distinct Patterns , Clinical Samples , Image Credit , Next Strain , Corona Virus , Coronavirus Disease Covid 19 , Genomic Sequencing , In Vitro , Sars Cov 2 , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , ஒன்றுபட்டது மாநிலங்களில் , ஒன்றுபட்டது கிஂக்டம் , தனித்துவமானது வடிவங்கள் , மருத்துவ மாதிரிகள் , படம் கடன் , அடுத்தது திரிபு , கொரோனா வைரஸ் , இல் விட்ரோ , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,

Study explores how choice of foods influences aging and lifespan in fruit flies

Study explores how choice of foods influences aging and lifespan in fruit flies
Having a choice of foods may accelerate aging and shorten the lifespan of fruit flies, according to a study published today in the open-access
eLife journal.
While early experiments have shown that calorie restriction can extend lifespan, the current study adds to the growing body of evidence that suggests other diet characteristics besides calories may also influence aging and lead to earlier death.
It has been recognized for nearly a century that diet modulates aging. For our study, we wanted to see if having a choice of foods affects metabolism and lifespan in the fruit fly Drosophila melanogaster. ....

Ann Arbor , United States , Yang Lyu , Scott Pletcher , Williamh Howell , Emily Henderson , Research Professor , University Of Michigan Medical School , Institute Of Gerontology , Department Of Molecular Integrative Physiology , First Author , Postdoctoral Fellow , Integrative Physiology , Michigan Medical School , Collegiate Professor , Michigan Medical , Medical School , ஆண்டு ஆர்பர் , ஒன்றுபட்டது மாநிலங்களில் , ஸ்காட் பிலேட்ச்சேர் , எமிலி ஹென்டர்சன் , ஆராய்ச்சி ப்ரொஃபெஸர் , பல்கலைக்கழகம் ஆஃப் மிச்சிகன் மருத்துவ பள்ளி , நிறுவனம் ஆஃப் ஜெரண்டாலஜி , துறை ஆஃப் மூலக்கூறு ஒருங்கிணைந்த உடலியல் , முதல் நூலாசிரியர் ,

Another new coronavirus variant found across California

LOS ANGELES — As the total number of coronavirus infections in California approaches 3 million, health officials said Sunday that a new strain — different from a highly contagious variant ....

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