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Freddie Mercury: "Ele viveu ao máximo cada segundo do dia", afirma Brian May

Freddie Mercury: "Ele viveu ao máximo cada segundo do dia", afirma Brian May
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London , City-of , United-kingdom , States-brian , For-matthew-brook , English-brian , Dies-freddie , லண்டன் , நகரம்-ஆஃப் , ஒன்றுபட்டது-கிஂக்டம் , மாநிலங்களில்-பிரையன்

Четверте самогубство поліцейського, який брав участь у захисті Капітолію

Четверте самогубство поліцейського, який брав участь у захисті Капітолію
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Washington , District-of-columbia , United-states , States-brian , Police-jeffrey-smith , Seconds-fourth , United-states-brian , வாஷிங்டன் , மாவட்டம்-ஆஃப்-கொலம்பியா , ஒன்றுபட்டது-மாநிலங்களில் , மாநிலங்களில்-பிரையன் , ஒன்றுபட்டது-மாநிலங்களில்-பிரையன்

Cenaberta apresenta ator selecionado para protagonizar "O Pequeno Príncipe no Cerrado"

Cenaberta apresenta ator selecionado para protagonizar "O Pequeno Príncipe no Cerrado"
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Brazil , Brazilian , States-brian , Theater-in-school , Small-prince , Profile-brian , University-federally , Pineapple-city , Show-one , பிரேசில் , பிரேசிலியன் , மாநிலங்களில்-பிரையன்

经基因工程改造的啤酒酵母或可用于检测和治疗肠道炎症

我们的肠道微生物组越来越多地与从癌症到神经退行性疾病等各种疾病有关，但目前仍不清楚我们如何将这些新发现转化为临床治疗。粪便移植可能是我们已经开发的最原始的微生物修改疗法，而益生菌只是依靠提高自然发生的细菌的特定水平。
在过去的几年里，各种初步研究已经证明了工程细菌可以杀死结肠直肠癌，治疗糖尿病，并清除多余的氨气。现在，发表在《自然医学》上的一项新研究正在证明一种CRISPR工程酵母菌如何能够检测肠道炎症并进行治疗。
"我们采取了酵母--用于制造啤酒的酵母--并赋予它感知炎症和分泌抗炎分子的能力，"通讯作者Francisco Quintana解释说。“我们把这个新平台称为'Y-bots'（酵母机器人），并在这里看到了开发能够治疗肠道组织等疾病的治疗方法的潜力。”
研究人员将这种工程酵母描述为 "可自我调整"的，这意味着其抗炎分子的分泌与不同的促炎分子的可检测水平直接相关。因此，假设这种细菌应该能够根据它在肠道中收到的信号提供局部的炎症治疗。没有炎症等于没有分泌药物，大量的炎症等于大量的抗炎代谢物。
与大多数这些工程细菌实验一样，该研究仍处于临床前阶段。新研究详细介绍了IBD小鼠模型的测试，显示工程酵母确实有效地抑制了肠道炎症，其疗效 "类似于或高于 "目前的治疗方法。但是到目前为止，还没有着手进行人体试验。
不过这类治疗方法离临床应用还有好几年的时间，其中许多甚至没有达到人类安全测试的阶段。然而，考虑到几十年后的医学会是什么样子，这些设计好的细菌给我们带来了一个迷人的未来主义想法。除了肠道炎症，假设细菌可以被改造成既能诊断许多疾病，又能产生任何数量的不同代谢物作为治疗。
Quintana说：“我们想利用合成生物学的工具来设计自然界中可以找到的东西。通过工程化益生菌，我们的目标是创造更加个性化、本地化和高度控制的药物，用于治疗肠道和其他方面的疾病。”
这项新研究发表在《自然医学》杂志上。

States-brian , Hospitala-research , United-states-brian , New-research , மாநிலங்களில்-பிரையன் , ஒன்றுபட்டது-மாநிலங்களில்-பிரையன் , புதியது-ஆராய்ச்சி ,

DigiCert traz a credibilidade da assinatura digital e a verificação remota de identidades de última geração para a assinatura de documentos

DigiCert traz a credibilidade da assinatura digital e a verificação remota de identidades de última geração para a assinatura de documentos
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States-brian , மாநிலங்களில்-பிரையன் ,

The Sleepless Unrest: Em documentário, grupo se hospeda na casa que inspirou o filme "Invocação do Mal", e grava acontecimentos sobrenaturais; assista ao trailer!

Filmes
The Sleepless Unrest: Em documentário, grupo se hospeda na casa que inspirou o filme “Invocação do Mal”, e grava acontecimentos sobrenaturais; assista ao trailer!
Kaynã de Oliveira - Publicado em
15/06/2021 às 18:37.
Compartilhe:
E vamos de susto! Nesta terça-feira (15), o site Bloody Disgusting divulgou um trailer exclusivo do documentário “The Sleepless Unrest”, que investiga acontecimentos paranormais na casa original da história do filme “Invocação do Mal”. Bem sabemos o peso da frase “baseado em fatos” nos filmes de terror, né?! Agora, imagina só ter a chance de conhecer o local que inspirou toda a trama! Fãs da franquia, se preparem!

Lorraine-warren , States-brian , Their-library , States-attached , For-the-time-being , லோரெய்ன்-வாரன் , மாநிலங்களில்-பிரையன் , அவர்களது-நூலகம் , க்கு-தி-நேரம்-இருப்பது ,

무례한 질문 재치로 받아쳐... "냄새 맡지 않아, 난 개가 아니다"

무례한 질문 재치로 받아쳐... "냄새 맡지 않아, 난 개가 아니다"
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United-states , United-kingdom , South-korea , Los-angeles , California , Korea , States-brian , United-states-los-angeles-union , Academy-award-for-best-supporting-actress , United-kingdom-academy , Academy-award , Best-supporting-actress

외신도 조명한 윤여정 "그는 노련한 신스틸러"

외신도 조명한 윤여정 "그는 노련한 신스틸러"
ohmynews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from ohmynews.com Daily Mail and Mail on Sunday newspapers.

United-states , United-kingdom , South-korea , Los-angeles , California , Korea , States-brian , Yoon-yeo-jeong , United-states-los-angeles-union , Academy-award-for-best-supporting-actress , United-kingdom-academy , Academy-award

무례한 질문 재치로 받아쳐... "냄새 맡지 않아, 난 개가 아니다"

무례한 질문 재치로 받아쳐... "냄새 맡지 않아, 난 개가 아니다"
ohmynews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from ohmynews.com Daily Mail and Mail on Sunday newspapers.

United-states , United-kingdom , South-korea , Los-angeles , California , Korea , States-brian , United-states-los-angeles-union , Academy-award-for-best-supporting-actress , United-kingdom-academy , Academy-award , Best-supporting-actress

Adolescente da região no Bolshoi fica cada vez mais perto do sonho de ser bailarino profissional

Adolescente da região no Bolshoi fica cada vez mais perto do sonho de ser bailarino profissional
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Russia , Brazil , Russian , Brazilian , Fernanda-soares , States-brian , Golini-states , School-russian , School-today , Brian-gilson , River-white , States-attached