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E-Mail A new study identifies a novel biomarker indicating resilience to chronic stress. This biomarker is largely absent in people suffering from major depressive disorder, and this absence is further associated with pessimism in daily life, the study finds. Nature Communications published the research by scientists at Emory University. The researchers used brain imaging to identify differences in the neurotransmitter glutamate within the medial prefrontal cortex before and after study participants underwent stressful tasks. They then followed the participants for four weeks, using a survey protocol to regularly assess how participants rated their expected and experienced outcomes for daily activities. ....
A new study identifies a novel biomarker indicating resilience to chronic stress. This biomarker is largely absent in people suffering from major depressive disorder, and this absence is further associated with pessimism in daily life, the study finds. Researchers used brain imaging to identify differences in the neurotransmitter glutamate within the medial prefrontal cortex before and after study participants underwent stressful tasks. They then followed the participants for four weeks, using a survey protocol to regularly assess how participants rated their expected and experienced outcomes for daily activities. “In many ways, depression is a stress-linked disorder.” “To our knowledge, this is the first work to show that glutamate in the human medial prefrontal cortex shows an adaptive habituation to a new stressful experience if someone has recently experienced a lot of stress,” says senior author Michael Treadway, professor in Emory University’s depar ....
The Good Men Project Become a Premium Member We have pioneered the largest worldwide conversation about what it means to be a good man in the 21st century. Your support of our work is inspiring and invaluable. How Your Brain Decides To Put in Effort Researchers have clear visual evidence that a region of the human brain known as the ventral striatum kicks in during decision-making to weigh the costs versus the benefits of making a physical effort.
The research gives the first detailed view of ventral striatum activity during three phases of effort-based decision-making the anticipation of initiating an effort, the actual execution of the effort, and the reward, or outcome, of the effort. ....
Government Executive email How Your Brain Decides to Put in Effort If you want more coffee, but the pot is empty, is it worth getting up and brewing some more? Researchers have figured out how your brain decides. Researchers have clear visual evidence that a region of the human brain known as the ventral striatum kicks in during decision-making to weigh the costs versus the benefits of making a physical effort. The research gives the first detailed view of ventral striatum activity during three phases of effort-based decision-making the anticipation of initiating an effort, the actual execution of the effort, and the reward, or outcome, of the effort. ....