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U.S. Justice Dept orders review that grantees obey civil rights laws

Associate Attorney General Vanita Gupta this week ordered the Justice Department to review whether it is adequately monitoring police departments and other recipients of its federal grants to ensure they are not engaging in "illegal discrimination."

Phoenix , Arizona , United-states , Washington , David-gregorio , Donald-trump , Sarahn-lynch , Vanita-gupta , Sherrilyn-ifill , George-floyd , Thomson-reuters-trust-principles , Justice-department

Massachusetts fines MassMutual $4.75 mln in 'Roaring Kitty' case

A MassMutual investment subsidiary has agreed to pay $4.75 million to resolve allegations by Massachusetts securities regulators including that it failed to supervise its agents, among them the social media persona "Roaring Kitty," whose online posts helped spark January's trading frenzy in GameStop Corp shares.

Massachusetts , United-states , Boston , Cynthia-osterman , Nate-raymond , Sonya-hepinstall , Keith-gill , Gamestop-corp , Thomson-reuters-trust-principles , Investors-services , Reuters , Gamestop

Frontiers | Significant Difference of Immune Cell Fractions and Their Correlations With Differential Expression Genes in Parkinson's Disease

Parkinson’s disease (PD) is the second most neurodegenerative disease in the world. T cell infiltration in the central nervous system (CNS) has provided insights that the peripheral immune cells participate in the pathogenesis of PD. However, the association between the peripheral immune system and CNS is remained to be elucidated. Here, we analyzed an incorporative substantial nigra expression data as well as another blood expression data using the CIBERSORT to obtain the 22 immune cells fraction and then explored the molecular function to identify the potential key immune cell types and genes of PD. We observed the proportions of naïve CD4 T cells, gamma delta T cells, resting NK cells, neutrophils in the blood, and regulatory T cells (Tregs) in the substantial nigra were significantly different between PD patients and healthy controls (HC). We identified p53-induced death domain protein 1 (PIDD1) as the hub gene of a Parkinson’s disease-related module. The set of neuron-specific genes was significantly different between PD and HC, and genes in the neuron-related module were enriched in the biological process about mitochondria and synapses. These results suggested that the fractions of naïve CD4 T cells, gamma delta T cells, resting natural killer (NK) cells, as well as neutrophils, may be used as a combined diagnostic marker in blood and Tregs in substantial nigra may be a potential therapeutic design target for PD.

China , Sanli , Shaanxi , United-states , Kyoto , Japan , Guangdong , Jilin , Chinese , J-neuroimmune-pharmacol , Felix-garza , Tregs-rosenkranz

Texas governor tests positive for COVID-19, has no symptoms

Texas Governor Greg Abbott, whose state is engulfed in a fourth COVID surge, tested positive for COVID-19 on Tuesday but so far has no symptoms of the illness, his office said.

Texas , United-states , New-york , Louisiana , New-orleans , Tampa , Florida , Hillsborough-county , Washington , Lubbock , Houston , Bangalore

U.S. probing Moderna vaccine for higher heart inflammation risk - Washington Post

U.S. health officials are investigating reports that Moderna Inc's COVID-19 vaccine may be linked to a higher risk of a rare heart condition in younger adults than previously thought, the Washington Post reported late on Thursday, citing people familiar with the review.

Canada , Bengaluru , Karnataka , India , Washington , United-states , Canadian , Shubham-kalia , Krishna-chandra-eluri , Thomson-reuters-trust-principles , Pfizer , Washington-post

中国电子烟龙头思摩尔期待政策落地后有一个比较明确的方向

中国电子烟雾化设备制造商--思摩尔国际<6969.HK>管理层周五表示，内地对电子烟加强监管的政策尚未明确，但相信政策明确的时间应愈来愈近，待政策落地后，相信市场会对整体电子烟市场及公司更有信心。

China , Hong-kong-august , Monopoly-bureau-country-market , Hong-kong-august-china , China-country , Management-general , Smoore , Miit , Regs , 0820 , Chinese-simplified- , சீனா

AstraZeneca's antibody therapy prevents COVID-19 in study

Trial data from AstraZeneca on Friday raised the prospect of a new treatment to prevent COVID-19 beyond vaccines, giving hope in particular for people who respond poorly to immunisation shots.

Sweden , Bengaluru , Karnataka , India , United-kingdom , British , Swedish , Ludwig-burger , Jason-neely , Sriraj-kalluvila , Thomson-reuters-trust-principles , Vanderbilt-university-medical-center

UK approves Regeneron/Roche antibody cocktail for COVID-19

The UK drug regulator has approved an antibody cocktail developed by Regeneron and Roche to prevent and treat COVID-19, it said on Friday, as the nation battles rising hospitalisations due to the more infectious Delta variant.

Japan , Bengaluru , Karnataka , India , United-kingdom , British , Sajid-javid , Jason-neely , Sachin-ravikumar , Thomson-reuters-trust-principles , Reuters , Regulatory-agency

Indian drug regulator panel recommends Cadila's COVID-19 vaccine - CNBC-TV18

The Indian drug regulator's subject expert committee has recommended emergency use approval for Zydus Cadila's three-dose COVID-19 vaccine, CNBC-TV18 reported on Friday, citing sources.

India , Bengaluru , Karnataka , Shivani-singh , Zydus-cadila , Thomson-reuters-trust-principles , Cadila-healthcare-ltd , Reuters , Bharat-biotech , Thomson-reuters-trust , Bact , Blr

Analysis: Green-push dilemma: China's steel curbs could cripple price control efforts

China is facing a high profile test of its commitment to curbing industrial pollution after steel output surged in the first half of the year to well beyond its target of capping production at 2020's peak, sending emissions to new highs.

Fujian , China , Tianjin , Beijing , Vietnam , Republic-of , Jinrui , Jiangxi , Guangdong , Jilin , Guangxi , Hebei