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Indiana lawmakers set to decide next two years of state spending over next two weeks


“I’ll see you in heaven.”
It was the last thing Al Braccolino, 90, of Crown Point, told one of his daughters as paramedics loaded him into an ambulance Nov. 16. COVID-19 forced him into the final fight of his life.
Ten days later, the chair Al usually occupied at the Thanksgiving table would sit empty. The husband to his wife of 70 years, father of three and grandfather of six died on the holiday.
Al’s daughter, Sandra Noe, was herself suffering from COVID-19, which she contracted while caring for her sick parents, when the virus forced Al’s hospitalization.
Noe, 66, is no stranger to helping elderly shut-ins weather isolation. ....

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Scientists compare DNA damaging properties of chemicals from vape products and cigarettes


Scientists compare DNA damaging properties of chemicals from vape products and cigarettes
Imperial Brands scientists have utilized Toxys ToxTracker suite of stem-cell based in-vitro assays, which provide mechanistic insight into the potential DNA damaging properties of chemicals, comparing vape e-liquid samples and their aerosols to combustible cigarette smoke.
Imperial scientists are the first to publish results using the ToxTracker system for the assessment of vape e-liquids and aerosols, and it forms part of the company s continuing research into the tobacco harm reduction potential of Next Generation Products (NGPs) such as vapes.
The assays help assess how product samples may impact cellular functioning across six reporter cell lines, picking up the tell-tale molecular signs of potential harm in the form of oxidative stress, DNA and protein damage, as well as activation of the p53 gene that has a role in cell cycle regulation and tumour suppression. ....

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RESEARCH: How long cannabis users are impaired or 'stoned'


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How long cannabis users stay impaired or stoned has been discovered by researchers at the Lambert Initiative for Cannabinoid Therapeutics, as medicinal cannabis prescriptions exceed 100,000 nationwide.
As legal cannabis is prescribed more regularly, lead researcher Dr Danielle McCarthy and associates conducted the most comprehensive study so far into cannabis impairment.
While the intoxicating ingredient in marijuana, THC, can be detected for weeks after consumption, researchers found people remained impaired for between three and 10 hours after consuming moderate to high doses of cannabis.
The Lambert Initiative for Cannabinoid Therapeutics was launched at Sydney University after Barry and Joy Lambert made a $33.7 million donation for research into the therapeutic use of medicinal cannabis. ....

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