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Top News In வாஸ்குலர் ஒட்டு பாலீயெஸ்‌டர் மனிதன் செய்து Today - Breaking & Trending Today

Scientists find new therapeutic approach to effectively treat age-related macular degeneration


Scientists find new therapeutic approach to effectively treat age-related macular degeneration
Runt-related transcription factor 1 (RUNX1) has been linked to retinal neovascularization and the development of abnormal blood vessels, which result in vision loss in diabetic retinopathy. Now, scientists have found that RUNX1 inhibition presents a new therapeutic approach in the treatment of age-related macular degeneration (AMD), which is the leading cause of blindness in the elderly worldwide. Their results are reported in
The American Journal of Pathology, published by Elsevier.
Abnormal growth of blood vessels, or aberrant angiogenesis, arises from the choroid, a part of the eye located behind the retina. This condition, known as choroidal neovascularization (CNV), is present in several ocular diseases that lead to blindness such as AMD. This study is the first to implicate RUNX1 in CNV and to test RUNX1 inhibition therapy for treating CNV. Researchers found that appli ....

United States , Leoa Kim , Lucia Gonzalez Buendia , Josephf Arboleda Velasquez , Emily Henderson , Schepens Eye Research Institute Of Mass , Puerta De Hierro Majadahonda University Hospital Spain , Harvard Medical School , Department Of Ophthalmology , American Journal , Puerta De Hierro Majadahonda University Hospital , Schepens Eye Research Institute , Mass Eye , Drug Administration Approved , Aassistant Scientist , Assistant Professor , Age Related Macular Degeneration , Macular Degeneration , Blood Vessels , Diabetic Retinopathy , Medical School , Vision Loss , ஒன்றுபட்டது மாநிலங்களில் , லூசியா கோன்சலஸ் பியூண்டியா , எமிலி ஹென்டர்சன் , திட்டங்கள் கண் ஆராய்ச்சி நிறுவனம் ஆஃப் நிறை ,

Understanding the dynamics of brain blood flow could hold key for treating neurologic conditions


Understanding the dynamics of brain blood flow could hold key for treating neurologic conditions
While the human brain has over 400 miles of total vasculature, little is known about the tiny capillaries that make up much of this intricate labyrinth of blood vessels critical for delivering oxygenated blood and nutrients to billions of brain cells.
According to Dr. Andy Shih, a principal investigator in the Center for Developmental Biology and Regenerative Medicine at Seattle Children s Research Institute, understanding how this vast network regulates blood flow in the brain could hold the key to new treatments for neonatal and childhood neurologic conditions, such as stroke and hypoxia, and issues of aging like dementia and Alzheimer s disease. ....

David Hartmann , Andy Shih , Andree Anne Berthiaume , Emily Henderson , Regenerative Medicine At Seattle Children Research Institute , Seattle Children Research Institute , Stanford University , Developmental Biology , Regenerative Medicine , Seattle Children , Research Institute , Study Principal Investigator , Nature Neuroscience , Juliane Gust , Alzheimer 39s Disease , Blood Vessels , Clinical Imaging , Imaging Techniques , In Vivo , Opto Genetics , டேவிட் ஹார்ட்மேன் , ஆண்டி ஷிஹ் , அன்றேல் அன்னே பெர்த்தியாம் , எமிலி ஹென்டர்சன் , மீளுருவாக்கம் மருந்து இல் சீட்டில் குழந்தைகள் ஆராய்ச்சி நிறுவனம் , சீட்டில் குழந்தைகள் ஆராய்ச்சி நிறுவனம் ,

COVID-19 and lung cancer have a common pathway, say researchers


COVID-19 and lung cancer have a common pathway, say researchers
The coronavirus disease 2019 (COVID-19) is a transmissible viral disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen responsible for the ongoing global pandemic. The virus was first detected in Wuhan, China, at the end of 2019 and to date has caused over 109 million infections worldwide.
With over 2.4 million deaths, this virus can cause severe disease in certain high-risk groups such as those with metabolic syndrome, diabetes, cardiovascular disease and an abnormally high body mass index (BMI). A new preprint on the
bioRxiv server describes the common features shared by this condition with lung cancer. ....

Liji Thomas , Coronavirus Disease Covid 19 , Lung Cancer , Sars Cov 2 , Body Mass Index , Cardiovascular Disease , Cell Migration , Cell Proliferation , Chronic Obstructive Pulmonary Disease , Corona Virus , Growth Factor , Immune Response , Metabolic Syndrome , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , Viral Disease , நுரையீரல் புற்றுநோய் , உடல் நிறை குறியீட்டு , இருதய நோய் , செல் இடம்பெயர்வு , நாள்பட்ட தடைசெய்யும் நுரையீரல் நோய் , கொரோனா வைரஸ் , நீரிழிவு நோய் , வளர்ச்சி காரணி , நோய் எதிர்ப்பு சக்தி பதில் , வளர்சிதை மாற்ற நோய்க்குறி ,

Study: Patients should be assessed for frailty before considering multiple surgeries


Study: Patients should be assessed for frailty before considering multiple surgeries
Patients should be assessed for frailty before having many types of surgery, even if the surgery is considered low risk, a review of two national patient databases shows.
Frailty is a clinical syndrome marked by slow walking speed, weak grip, poor balance, exhaustion and low physical activity. It is an important risk factor for death after surgery, although the association between frailty and mortality across surgical specialties is not well understood.
The study, conducted by faculty at multiple institutions including The University of Texas Health Science Center at San Antonio (UT Health San Antonio), mined patient data from the Veterans Affairs (VA) Surgical Quality Improvement Program and the American College of Surgeons (ACS) National Surgical Quality Improvement Program. ....

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