Since opening her first storefront in Chicago’s Gold Coast neighborhood in 2001, Ikram Goldman has single handedly put America’s Second City on the fashion map. Her eponymous boutique, which moved to a bigger location in 2011, is home to some of the world’s most illustrious designers and their straight-off-the-runway designs–Goldman’s brand roster includes Comme des Garçons, Sacai, Givenchy, Valentino, Fendi, Stella McCartney, and more. Inside her lacquered, crimson-splashed shop with giant porthole windows, you’ll find rows of mannequins dressed in nothing but strands of statement necklaces, as well as a second floor stocked with clothes, gifts, and accessories, as well as a farm-to-table cafe. —Brooke Bobb