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Researchers Identify a New, Vital Player in Graft-Versus-Host Disease and Organ Transplant Rejection

Researchers Identify a New, Vital Player in Graft-Versus-Host Disease and Organ Transplant Rejection
How one long noncoding RNA could help improve outcomes in bone marrow and solid organ transplantation.
Credit: Michigan Medicine
A long noncoding RNA whose function was previously unknown turns out to play a vital role in mobilizing the immune response following a bone marrow transplant or solid organ transplantation.
This RNA molecule, cataloged in scientific databases simply as Linc00402, helps activate immune defenders known as T cells in response to the presence of foreign human cells, according to a new study by researchers at the University of Michigan Rogel Cancer Center and Michigan Medicine. ....

United States , Daniel Peltier , Pavan Reddy , University Of Michigan Rogel Cancer Center , Rogel Cancer Center , Michigan Rogel Cancer Center , Science Translational , ஒன்றுபட்டது மாநிலங்களில் , டேனியல் பெழ்திிேர் , பவன் சிவப்பு , பல்கலைக்கழகம் ஆஃப் மிச்சிகன் ரோஜல் புற்றுநோய் மையம் , ரோஜல் புற்றுநோய் மையம் , மிச்சிகன் ரோஜல் புற்றுநோய் மையம் , அறிவியல் மொழிபெயர்ப்பு ,

A new, vital player in graft-versus-host disease and organ transplant rejection

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A long noncoding RNA whose function was previously unknown turns out to play a vital role in mobilizing the immune response following a bone marrow transplant or solid organ transplantation.
This RNA molecule, cataloged in scientific databases simply as Linc00402, helps activate immune defenders known as T cells in response to the presence of foreign human cells, according to a new study by researchers at the University of Michigan Rogel Cancer Center and Michigan Medicine.
The investigation, which included samples from more than 50 patients who underwent a bone marrow or heart transplant, suggests inhibiting the RNA therapeutically might improve outcomes for transplant recipients. Their findings appear in ....

Michigan Center , United States , Cynthia Zajac , Julia Wu , Guoqing Hou , Visweswaran Ravikumar , Hideaki Fujiwara , Austin Taylor , Daniel Goldstein , Stephanie Kim , Molly Radosevich , Sherric Wood , Thomas Decoville , David Sokol , Arvind Rao , Pavan Reddy , Yaping Sun , Arul Chinnaiyan , Katherine Oravecz Wilson , Daniel Peltier , Sethuramasundaram Pitchiaya , Baldrick Foundation Fellowship , National Institutes Of Health , Rogel Cancer Center , University Of Michigan Rogel Cancer Center , Department Of Defense Idea Development Award ,

A new, vital player in graft-versus-host disease and organ transplant rejection

A new, vital player in graft-versus-host disease and organ transplant rejection
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Michigan Center , United States , Cynthia Zajac , Julia Wu , Guoqing Hou , Visweswaran Ravikumar , Hideaki Fujiwara , Austin Taylor , Daniel Goldstein , Stephanie Kim , Molly Radosevich , Sherric Wood , Thomas Decoville , David Sokol , Arvind Rao , Pavan Reddy , Yaping Sun , Arul Chinnaiyan , Katherine Oravecz Wilson , Daniel Peltier , Sethuramasundaram Pitchiaya , Baldrick Foundation Fellowship , National Institutes Of Health , Rogel Cancer Center , University Of Michigan Rogel Cancer Center , Department Of Defense Idea Development Award ,

Volume 62, Issue 1 | Mass Review

Brooklyn, NY, June 19, 2020.
Volume 62, Issue 1
SPRING FORWARD, FALL BACK. As mnemonics go, one of the best, as equipment for living, not the recipe we need. Though this issue hits the bookstands the day after we spin the clocks ahead, if springing forward is what you’re looking for, you’ve come to the wrong place. Many things must change, given where we’ve been, yet none of that will happen unless we come to terms with what we’ve learned. And it isn’t the lies, the self-dealing, the rancor, or even, at some level, the damage done, the lives ended, the fortunes ruined, the friends and family lost. All of that still burns, how could it not, and nothing will be forgotten, because how could it be? Yet what is truly essential, what must at last be confronted, was delivered to us drop by drop during this interminable succession of isolated days, a truth that 2020 hindsight cannot not reveal. Though elsewhere there will be other versions, in the US that truth is simple ....

United States , Czech Republic , Washington University , University Of Virginia , Black Warrior , Hampshire College , Rice University , Los Angeles , City Of , United Kingdom , Comunidad Autonoma De Extremadura , Western Michigan University , White House , District Of Columbia , Stanford University , Western Cape , South Africa , University Of Colorado Denver , Diamond Square , Comunidad Autonoma De Cataluna , Ursa Minor , University Of Massachusetts , Rostovskaya Oblast , Champagne Ardenne , Al Iskandariyah , France General ,

Oncocyte Announces Formation of Medical Advisory Board

Oncocyte Announces Formation of Medical Advisory Board
globenewswire.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from globenewswire.com Daily Mail and Mail on Sunday newspapers.

University Of Southern California , United States , Heinz Josef Lenz , Fredr Hirsch , Joe Lowe , Danielf Hayes , Ignacioi Wistuba , Doug Ross , David Gandara , Bob Yedid , Division Of Cancer Medicine , Department Of Translational Molecular Pathology , Lung Committee For Southwest Oncology Group , American Society Of Clinical Oncology , Leader Of The Gastrointestinal Cancers Program , National Cancer Institute , Egi Committee , Md Anderson Cancer Center , Tisch Cancer Institute At Mount Sinai , University Of Michigan , Division Head , Oncocyte Corporation , Lenz Is Co , Department Of Thoracic Head , Division Of Medical Oncology , Clinical Research ,