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Startups bet that carefully controlled cell reprogramming may lead to age reversal, but hurdles remain

CARY INSURRECTIONIST BACK WHERE HE BELONGS, IN FEDERAL CUSTODY: On Jan. 6, 2021, when prosecutors say James Grant led the first assault on the U.S. Capitol, the North Carolina man wore a baseball cap with an insignia that bore a map of his home state, along with these words: “Drink Local.” Last month, Grant did just that. Now he’s going back to jail. On Dec. 7, after a bizarre

Gene Editing Expands to New Types of Immune Cells Gladstone researchers fine-tuned CRISPR-Cas9 genome editing to work on human immune cells called monocytes News provided by Share this article Share this article SAN FRANCISCO, May 11, 2021 /PRNewswire/ -- In the decade since the advent of CRISPR-Cas9 gene editing, researchers have used the technology to delete or change genes in a growing number of cell types. Now, researchers at Gladstone Institutes and UC San Francisco (UCSF) have added human monocytes—white blood cells that play key roles in the immune system—to that list. A team of sc...

New method helps map the specialized diversity and spatial location of cells within a tissue or tumor Not all cancer cells within a tumor are created equal; nor do all immune cells (or all liver or brain cells) in your body have the same job. Much of their function depends on their location. Now, researchers at Gladstone Institutes, UC San Francisco (UCSF), and UC Berkeley have developed a more efficient method than ever before to simultaneously map the specialized diversity and spatial location of individual cells within a tissue or a tumor. The technique, called XYZeq, was described online ...

 E-Mail SAN FRANCISCO, CA--April 21, 2021--Not all cancer cells within a tumor are created equal; nor do all immune cells (or all liver or brain cells) in your body have the same job. Much of their function depends on their location. Now, researchers at Gladstone Institutes, UC San Francisco (UCSF), and UC Berkeley have developed a more efficient method than ever before to simultaneously map the specialized diversity and spatial location of individual cells within a tissue or a tumor. The technique, called XYZeq, was described online this week in the journal Science Advances. It involves se...