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In the largest study of its kind.11 prostate cancer genes were discovered for the first time

Scientists have discovered nearly a dozen genes linked to aggressive prostate cancer in the largest study of its kind.Roughly one in eight American men will be struck by prostate cancer in their lives, making it the most commonly diagnosed men’s cancer, s ....

United States , United Kingdom , Robert De Niro , Burcu Darst , Christopher Haiman , Warren Buffett , University Of Southern California , Southern California ,

Mutations in 11 genes associated with aggress

An international research team led by USC scientists has singled out mutations in 11 genes that are associated with aggressive forms of prostate cancer in the largest-scale prostate cancer study ever exploring the exome the key sections of the genetic code that contain the instructions to make proteins. The researchers analyzed samples from about 17,500 prostate cancer patients. They also found some genes that are currently part of such panels are not linked with risk for aggressive disease. The eleven genes that emerged as having mutations significantly linked to aggressive prostate cancer include BRCA2, also known for its connection to breast cancer. These eleven genes, as well as those currently screened in genetic tests found not to be linked serious disease, could influence individualized treatment for prostate cancer, as well as screening. ....

United States , City Of , United Kingdom , South Australia , Lucy Xia , Burcu Darst , David Conti , Xin Sheng , Loreall Pooler , Christopher Haiman , Public Health Sciences , Northwestern University , Aarhus University , University Of Texas Md Anderson Cancer Center , University Of Cambridge , Keck School , Norris Comprehensive Cancer Center , Method Of Research , National Institutes Of Health , Cancer Epidemiology Program , Fred Hutchinson Cancer Center , Institute Of Cancer Research , Cancer Research , University Of Oxford , Dana Farber Cancer Institute , Johns Hopkins University ,