Mutations in 11 genes associated with aggress : vimarsana.co

An international research team led by USC scientists has singled out mutations in 11 genes that are associated with aggressive forms of prostate cancer in the largest-scale prostate cancer study ever exploring the exome — the key sections of the genetic code that contain the instructions to make proteins. The researchers analyzed samples from about 17,500 prostate cancer patients. They also found some genes that are currently part of such panels are not linked with risk for aggressive disease. The eleven genes that emerged as having mutations significantly linked to aggressive prostate cancer include BRCA2, also known for its connection to breast cancer. These eleven genes, as well as those currently screened in genetic tests found not to be linked serious disease, could influence individualized treatment for prostate cancer, as well as screening.

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