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Glucagon-like peptide 1 receptor agonist use and risk of thyroid cancer: Scandinavian cohort study

Objective To investigate whether use of glucagon-like peptide 1 (GLP1) receptor agonists is associated with increased risk of thyroid cancer.

Design Scandinavian cohort study.

Setting Denmark, Norway, and Sweden, 2007-21.

Participants Patients who started GLP1 receptor agonist treatment were compared with patients who started dipeptidyl peptidase 4 (DPP4) inhibitor treatment, and in an additional analysis, patients who started sodium-glucose cotransporter 2 (SGLT2) inhibitor treatment.

Main outcome measures Thyroid cancer identified from nationwide cancer registers. An active-comparator new user study design was used to minimise risks of confounding and time related biases from using real world studies of drug effects. Cox regression was used to estimate hazard ratios, controlling for potential confounders with propensity score weighting.

Results The mean follow-up time was 3.9 years (standard deviation 3.5 years) in the GLP1 receptor agonist group an ....

United States , Karolinska Institutet , Eli Lilly , Drottning Victorias Frimurarestiftelse , Konung Gustaf , Swedish Research Council , European Medicines Agency , Lundbeck Foundation , Drug Administration , Danish Cancer Society , Swedish Cancer Society , Boehringer Ingelheim , Novo Nordisk Foundation , World Health Organization , Research Foundation Denmark , Novo Nordisk , Independent Research Foundation Denmark , Merck Sharp , Open Access , Creative Commons Attribution ,

Longer exclusive breastfeeding may lower risk for childhood hematologic cancers

Longer exclusive breastfeeding may lower risk for childhood hematologic cancers
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

Signe Holst , Helend Bailey , Danish Cancer Society , Danish National Child Health Register , Danish National Child Health , Exclusive Breastfeeding Duration , Childhood Cancers , Exploring Exclusive Breastfeeding , Childhood Cancer Using Linked Data ,

Breastfeeding Tied to Reduced Childhood Leukemia Risk

Lower pediatric ALL risk in Danish study when mothers exclusively breastfed for 3 months or more ....

Western Australia , United States , Mike Bassett , Signe Holst , Helend Bailey , Curtin University , Danish National Child Health Register , Danish Cancer Society , Danish Cancer Institute ,

A Painting by Denmark's Queen Margrethe II Heads to Auction

A painting by Denmark's longest reigning monarch will go up for sale in March. ....

United Kingdom , Bruun Rasmussen , Niels Boe Hauggaard , Palazzo Massimo , Ingahild Grathmer , Arken Museum , Danish Multiple Sclerosis Society , Denmark Arken Museum , Court Marshall , Danish Cancer Society , University Of Cambridge , Courtesy Bruun , Queen Margrethe , New Year , Wild Swan , Wild Swans ,

Menopausal hormone therapy and central nervous system tumors: Danish nested case-control study

In this Danish nested case-control study, Nelsan Pourhadi and colleagues investigate the influence of the progestin-component of menopausal hormone therapy on central nervous system tumors. ....

United States , Wei Zheng , R Statistical Software , Danish Data Protection Agency , Vanderbilt University School Of Medicine , Danish Cancer Society , Health Insurance Denmark , National Prescription Registry , International Classification Of Diseases , Novo Nordisk , Danish Health Data Authority , Nordic Pharmacoepidemiological Network Norpen , European Union , Danish Cancer Society Scientific Committee , Danish Society For Pharmacoepidemiology , National Patient Registry , Danish Health Data Board , Rr Core Team , Danish Cancer Registry International Classification Of Diseases , Vanderbilt University School , Creative Commons Attribution License , General Data Protection Regulation , Health Insurance , Scientific Committee , Vice Chair , Danish Society ,