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miR-765 Acts as a Tumor Promoter and Indicates Poor Prognosis in Non-S

2
1Department of Oncology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, 200433, People’s Republic of China;
2Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, People’s Republic of China
*These authors contributed equally to this work
Purpose: Non-small cell lung cancer (NSCLC) is one of the leading causes of cancer-related death worldwide with poor prognosis. Accumulating evidence indicates that miR-765 is an important regulator in the progression and prognosis of various cancers. In this study, the function in the progression and prognosis of NSCLC was investigated.
Patients and Methods: The expression of miR-765 in NSCLC was analyzed by qRT-PCR. The effect of miR-765 on cell proliferation, migration, and invasion of NSCLC was evaluated by CCK8 and Transwell assay. Kaplan–Meier analysis and Cox regression analysis were employed to assess the prognostic value of mi ....

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Anti-triple negative breast cancer effects of doxcetaxel

Anti-triple negative breast cancer effects of doxcetaxel
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The roles of circRNAs in neuroblastoma

CircRNA-TBC1D4, circRNA-NAALAD2 and circRNA-TGFBR3: selected key circRNAs in neuroblastoma and their associations with clinical features ....

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LNC00115 mediates cisplatin resistance - CMAR

The mechanism by which the LNC00115/miR-7/ERK axis promotes cisplatin resistance provides a new strategy for combating cisplatin resistance in ovarian cancer ....

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A High Efficiency One-For-All Nanodroplet for Ultrasound

Supporting Information) under laser irradiation and resulted in PTT of the cancer cells (Figures 5, 6, and 8E). Secondly, the photothermally generated microbubbles enhanced acoustic cavitation (Figures 4 and 6D), their mechanical effects are able to destroy adjacent cancer cells and cause cell death (Figures 6A and 8E). Thus, the combination of PTT and cavitation-mediated cell destruction significantly improved the therapeutic outcomes as compared to the PTT alone (Figures 5, 6 and 8).
Conclusion
A “one-for-all” theranostic [email protected] nanodroplet with low-boiling PFP as the core and PPy that exhibited broad optical absorption constituting the shell was successfully constructed. The [email protected] nanodroplets represent an efficient PTT agent with outstanding photothermal conversion properties that can efficiently transfer NIR light into local hyperthermia for photothermal ablation of tumors. Meanwhile, the liquid-gas phase transition of the PFP cores was al ....

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