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Three-quarters of the last 16 qualifiers are already known, but Tottenham go to Marseille desperate to join them. And Man Utd need to score goals in Spain...
Portuguese clubs are thriving but Spanish sides have reached a historic low. Jurgen Klopp and Liverpool have taken a welcome step back.
Liverpool and Tottenham need a Champions League confidence boost, while Erik ten Hag has a massive decision to make over Cristiano Ronaldo.
In four days, Cristiano Ronaldo has gone from almost certainly having played his last Man Utd match to being an apology away from returning.
Liverpool v City; Steven Gerrard facing Chelsea with his job on the line; battle of the Brunos at Old Trafford; Arsenal at Leeds; El Clasico.