Page 145 - Genetic Algorithm News Today : Breaking News, Live Updates & Top Stories | Vimarsana

Stay updated with breaking news from Genetic algorithm. Get real-time updates on events, politics, business, and more. Visit us for reliable news and exclusive interviews.

Top News In Genetic Algorithm Today - Breaking & Trending Today

Study shows how mutant huntingtin protein triggers brain cell death


Study shows how mutant huntingtin protein triggers brain cell death
In 1993, scientists discovered that a single mutated gene, HTT, caused Huntington s disease, raising high hopes for a quick cure. Yet today, there s still no approved treatment.
One difficulty has been a limited understanding of how the mutant huntingtin protein sets off brain cell death, says neuroscientist Srinivasa Subramaniam, Ph.D., of Scripps Research, Florida.
In a new study published in
Nature Communications on Friday, Subramaniam s group has shown that the mutated huntingtin protein slows brain cells protein-building machines, called ribosomes.
The ribosome has to keep moving along to build the proteins, but in Huntington s disease, the ribosome is slowed. The difference maybe two, three, four-fold slower. That makes all the difference. ....

United States , Srinivasa Subramaniam , Emily Henderson , Scripps Research , Scripps Research Institute , Nature Communications On , Nature Communications , Huntington 39s Disease , Brain Cell , Cell Death , Protein Synthesis , ஒன்றுபட்டது மாநிலங்களில் , ஸ்ரீநிவாச சுப்ரமணியம் , எமிலி ஹென்டர்சன் , ஸ்கிரிப்ட்கள் ஆராய்ச்சி , ஸ்கிரிப்ட்கள் ஆராய்ச்சி நிறுவனம் , இயற்கை தகவல்தொடர்புகள் ஆன் , இயற்கை தகவல்தொடர்புகள் , மூளை செல் , செல் இறப்பு , ப்ரோடீந் தொகுப்பு ,

Researchers find new way to prevent attention deficits associated with Fragile X syndrome


Researchers find new way to prevent attention deficits associated with Fragile X syndrome
Mount Sinai Researchers find a new way to prevent attention deficits associated with Fragile X, a leading genetic cause of autism, in an animal model.
Corresponding author:
Hirofumi Morishita, MD, Ph.D., Department of Psychiatry, Neuroscience, Friedman Brain Institute, Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York.
Bottom line:
The adolescent maturation of the frontal cortex is important for establishing cognitive function, and disruption of this process is associated with neurodevelopmental disorders.
This study uncovered a new molecular driver of frontal circuit maturation that is essential for cognitive function, and demonstrated, in an animal model, that this mechanism can be targeted to restore attention deficits caused by a leading genetic cause of autism. ....

New York , United States , Hirofumi Morishita , Emily Henderson , Icahn School Of Medicine At Mount Sinai , Mount Sinai School Of Medicine , Development Institute , Mindich Child Health , Friedman Brain Institute , Department Of Psychiatry , Sinai Researchers , Icahn School , Mount Sinai , Mount Sinai School , Animal Model , Child Health , Cognitive Function , Fragilex Syndrome , Mouse Model , Top Down , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , ஹிரோபூமி மோரிஷிதா , எமிலி ஹென்டர்சன் , இக்ஹ்ன் பள்ளி ஆஃப் மருந்து இல் ஏற்ற சினை , ஏற்ற சினை பள்ளி ஆஃப் மருந்து ,

Interaction between LDL cholesterol and PRS can predict risk of heart attack


Interaction between LDL cholesterol and PRS can predict risk of heart attack
Allelica, a leading genomics software company specializing in developing polygenic risk scores (PRS) for personalized medicine, today announced publication of a study in
Circulation (Vol. 143, Issue 10) showing that the effect of LDL cholesterol on a person s risk of having a heart attack depends on their genes.
Using Allelica s proprietary PRS analysis software, the data showed that combining information on an individual s genetic risk of heart attack with their LDL level helps determine those at most risk from heart attack, including those potentially in need of treatment with statins or PCSK9 inhibitors. ....

Giordano Bott , George Busby , Emily Henderson , Coronary Artery Disease , United Kingdom , Heart Attack , ஜியோர்டானோ பாட்டில் , ஜார்ஜ் பஸ்பி , எமிலி ஹென்டர்சன் , கரோனரி தமனி நோய் , ஒன்றுபட்டது கிஂக்டம் , இதயம் தாக்குதல் ,