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SARS-CoV-2 variants rapidly arise in non-human hosts, potential risk for human reinfection

The study, published on the preprint server bioRxiv , highlights the need to study viral evolution and pathogenesis in human and animal hosts. This could help prevent future outbreaks that may mimic the magnitude of the current COVID-19 pandemic. ....

Saudi Arabia , United States , Angela Betsaidab Laguipo , University Of Pennsylvania School Veterinary Medicine , Researchers At Colorado State University , Angela Betsaida , Wuhan City , Colorado State University , Pennsylvania School , Veterinary Medicine , Middle East , Image Credit , Sars Cov 2 , Corona Virus , Coronavirus Disease Covid 19 , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , சவுதி அரேபியா , ஒன்றுபட்டது மாநிலங்களில் , பல்கலைக்கழகம் ஆஃப் பென்சில்வேனியா பள்ளி கால்நடை மருந்து , ஆராய்ச்சியாளர்கள் இல் கொலராடோ நிலை பல்கலைக்கழகம் , கொலராடோ நிலை பல்கலைக்கழகம் , பென்சில்வேனியா பள்ளி , கால்நடை மருந்து , நடுத்தர கிழக்கு , படம் கடன் ,

SARS-CoV-2 UK variant could soon be dominant in Switzerland

Researchers at the Swiss Institute of Bioinformatics estimate that the B.1.1.7 variant may be dominant in Switzerland by March. ....

United States , South Africa , United Kingdom , South African , Angela Betsaidab Laguipo , Swiss Institute Of Bioinformatics , World Health Organization , Angela Betsaida , Swiss Institute , Image Credit , Coronavirus Disease Covid 19 , Genomic Sequencing , Sars Cov 2 , Corona Virus , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , ஒன்றுபட்டது மாநிலங்களில் , ஒன்றுபட்டது கிஂக்டம் , சுவிஸ் நிறுவனம் ஆஃப் உயிர் தகவலியல் , உலகம் ஆரோக்கியம் ஆர்கநைஸேஶந் , சுவிஸ் நிறுவனம் , படம் கடன் , உயிர் தகவலியல் , கொரோனா வைரஸ் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,

New molecule passes toxicology testing to treat multiple sclerosis

Brazilian researchers who study a native venomous fish have confirmed a route to drug development for the treatment of chronic inflammatory diseases such as multiple sclerosis and asthma. ....

Lopes Ferreira , Emily Henderson , Dissemination Centers Ridcs , Brazilian Multiple Sclerosis Association , Paulo Research Foundation , Butantan Institute Special Laboratory For Applied Toxinology , Research On Toxins , Zebrafish Network , South Asia , Butantan Institute , Special Laboratory , Applied Toxinology , Immune Response , Cell Signaling , Dissemination Centers , Toxicology Reports , Carla Lima , Zebrafish Platform , Multiple Sclerosis , Animal Model , Anti Inflammatory , In Vivo , லோப்ஸ் ஃபெரீரா , எமிலி ஹென்டர்சன் , பிரேசிலியன் பல ஸ்க்லரோசிஸ் சங்கம் , பாலொ ஆராய்ச்சி அடித்தளம் ,

Researchers confirm new drug development route for treating multiple sclerosis, asthma

Researchers confirm new drug development route for treating multiple sclerosis, asthma
Brazilian researchers who study a native venomous fish have confirmed a route to drug development for the treatment of chronic inflammatory diseases such as multiple sclerosis and asthma.
The venomous toadfish Thalassophryne nattereri contains a peptide (TnP) with anti-inflammatory and anti-allergic potential. Confirmation of this potential has now come via the zebrafish Danio rerio, a popular aquarium species native to South Asia that shares 70% of its genome with humans and is widely used as a model for in vivo trials in drug development.
The researchers tested TnP in D. rerio to measure its toxicity. In a little over a year, their research showed that the peptide is safe. It did not cause cardiac dysfunction or neurological problems in the toxicity tests they performed. ....

Lopes Ferreira , Emily Henderson , Dissemination Centers Ridcs , Brazilian Multiple Sclerosis Association , Paulo Research Foundation , Butantan Institute Special Laboratory For Applied Toxinology , Research On Toxins , Zebrafish Network , South Asia , Butantan Institute , Special Laboratory , Applied Toxinology , Immune Response , Cell Signaling , Dissemination Centers , Toxicology Reports , Carla Lima , Zebrafish Platform , Multiple Sclerosis , Animal Model , Anti Inflammatory , In Vivo , லோப்ஸ் ஃபெரீரா , எமிலி ஹென்டர்சன் , பிரேசிலியன் பல ஸ்க்லரோசிஸ் சங்கம் , பாலொ ஆராய்ச்சி அடித்தளம் ,

RNA editing events influence gene expression and phenotypic manifestation

RNA editing events influence gene expression and phenotypic manifestation
Combining computational mining of big data with experimental testing in the lab, researchers at Children s Hospital of Philadelphia (CHOP) have identified RNA editing events that influence gene expression and, in turn, the phenotypic manifestation of that expression.
In analyzing so-called A-to-I RNA editing, in which the adenosine of an RNA molecule is chemically modified into an inosine, the researchers describe how a single nucleotide change by RNA editing can have large downstream effects. The findings were published today in
Genome Biology.
Millions of A-to-I RNA editing sites have been identified across the human transcriptome, but the functions of most RNA editing events are unknown. Understanding how RNA editing affects gene expression and phenotype could help us unravel the genetic basis to many human conditions. ....

United States , Emily Henderson , Study Senior Author , Genomic Medicine , Tissue Expression , Gene Expression , ஒன்றுபட்டது மாநிலங்களில் , எமிலி ஹென்டர்சன் , படிப்பு மூத்தவர் நூலாசிரியர் , திசு வெளிப்பாடு , கீந் வெளிப்பாடு ,