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Frontiers | Two major chromosome evolution events with unrivaled conserved gene content in pomegranate

Pomegranate has a unique evolutionary history given that different cultivars have eight or nine bivalent chromosomes with possible crossability between the two classes. Therefore, it is important to study the chromosome evolution in pomegranate to understand the dynamics of its population. Here, we de-novo assembled the Azerbaijanian cultivar “Azerbaijan guloyshasi“ (AG2017; 2n=16) and re-sequenced six cultivars to track the evolution of pomegranate, and to compare it with previously published de-novo assembled and re-sequenced cultivars. High synteny was observed between AG2017, Bhagawa (2n=16) and Tunisia (2n=16) to Dabenzi (2n=18), but these four cultivars were diverged from the cultivar Taishanhong (2n=18) with several rearrangements indicating the presence of two major chromosome evolution events. Major presence/absence variations were not observed as >99% of the five genomes aligned across the cultivars, while >99% of the pan-genic content was represented by Tunisia and ....

South Korea , Zuid Holland , United States , San Diego , North Yorkshire , United Kingdom , City Of , Noord Brabant , Vologodskaya Oblast , Sverdlovskaya Oblast , Republic Of Azerbaijan , D Boca Raton , Roopa Sowjanya , Indianj Hortic , Press Taylor , Agilent Tapestation , Bhagawa Punica , Augustus Stanke , Santa Clara , Mount Tai , Acta Hortic , Genetic Resources Institute , Francis Group , Lawrence Berkeley National Laboratory , Dna Library Prep , Office Of Science User Facility ,

T-cell Therapy Global Market Report 2023: Rising Global

Dublin, March 13, 2023 (GLOBE NEWSWIRE) The "T-cell Therapy Market Size, Share & Trends Analysis Report By Modality, By Therapy (CAR T-cell,. ....

United States , Gilead Sciences , Celgene Corporation , Research Methodology , Leukemia Lymphoma Society , Indication Movement Analysis , Therapy Type Movement Analysis , Merck Kga , Pfizer Inc , Therapeutics Inc , Merck Kgaa , American Society Of Hematology Annual Meeting Exposition , Modality Movement Analysis , Therapy Market Size , Trends Analysis Report By Modality , Tumor Infiltrating Lymphocytes , Hematologic Malignancies , Segment Forecasts , Lymphoma Society , American Society , Hematology Annual Meeting , Adoptivet Cell Transfer Approaches , Yescarta Across Various , Cart Cell Therapy , Ethical Challenges Associated With Gene , Global Investments ,

Uncovering the role of the genome in disease prevention

The field of genomics has grown exponentially over the last twenty years, largely due to the rapid development of methods like NGS, making DNA sequencing accessible to smaller institutions and not just large genome centres. Click to read more. ....

Czech Republic , Integra Biosciences , Department Of Biology , University Of Ostrava ,

Biden Budget Proposal Includes Billions for Cancer Moonshot

President Joe Biden s 2024 budget proposal includes a hefty investment in cancer prevention and treatment. ....

Environmental Protection Agency , District Of Columbia , United States , White House , Joe Biden , Centers For Disease , Research Projects Agency On Health , National Cancer Institute , Human Services , Drug Administration , Department Of Health , Department Of Veterans Affairs , Colorectal Cancer Control Program , National Breast , President Joe Biden , Cancer Moonshot , Disease Control , Veterans Affairs , Cancer Genomics , Cervical Cancer Early Detection Programs , Advanced Research Projects Agency , Cervical Cancer , Alignant Cervix Neoplasm , Alignant Neoplasia , Colorectal Cancer , Colorectal Cancer Screening ,

Active disease process in early CTE differs substantially from late-stage disease

Millions of people, including athletes who play contact sports, members of the military and victims of domestic violence, are exposed to repetitive head impacts (RHI), which is the primary risk factor for developing chronic traumatic encephalopathy (CTE). ....

United States , Thor Stein , Adam Thomas Labadorf , Emily Henderson , Brain Bank , Boston University Chobanian Avedisian School Of Medicine , Boston University Chobanian , Avedisian School , Thomas Labadorf , Industry Focus , Healthcare System , Lzheimer 39s Disease , Ene Expression ,