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Both Parotid and Labial Gland Biopsies Can Diagnose SjS

Although largely similar, some important histopathologic differences were seen in the biopsies of the labial and parotid salivary glands in individuals with suspected SjS.

Netherlands , Groningen , Uzma-nakshbandi , University-medical-center-groningen , Department-of-reumatology-clinical-immunology , Clinical-immunology , Sjogren-039s-syndrome , Jogren-syndrome , Mucosa-associated-lymphoid-tissue , Alt-mucosa-associated-lymphoid-tissue , Ucosa-associated-lymphatic-tissue , Glands

Comorbidities Weigh Heavily in Autoimmune Pregnancy Outcomes

After controlling for other chronic conditions, certain immune-mediated inflammatory diseases were not associated with an increased risk for poor pregnancy outcomes.

North-carolina , United-states , Duke-university-medical-center , Seattle , Washington , Catherine-sims , Jennifer-hadlock , Providence-st-joseph-health , Institute-for-systems-biology-in-seattle , Systems-biology , Large-study , Pregnancy

ACR Issues Guideline for Managing ILD in Rheumatic Disease

"Guidance was needed for which tests to use for screening and monitoring this particular disease," said lead author Sindhu R. Johnson, MD, PhD. The full manuscript will be published by early 2024.

New-york , United-states , Canada , California , Toronto , Ontario , American , Elizabeth-volkmann , Los-angeles , Elana-bernstein , Sindhur-johnson , University-of-toronto

Dazodalibep May Mitigate Sjögren Syndrome

The novel agent targets CD40 ligand and showed promising results in a two-stage, phase 2 clinical trial, particularly for patients with notable symptom burden but limited systemic organ involvement.

Milan , Lombardia , Italy , Chiara-baldini , Viela-bio , University-of-pisa , Systemic-involvement , European-alliance-of-associations , Newcastle-university , American-college-of-rheumatology , European-alliance , Horizon-thereapeutics

Remibrutinib Safe for Sjögren's in Phase 2

Results show the Bruton tyrosine kinase inhibitor has potential to become the first effective oral disease-modifying therapy for Sjögren syndrome.

Germany , New-york , United-states , Berlin , Philadelphia , Pennsylvania , Roche-genentech , Chrisanna-dobrowolski , Eli-lilly , Bristol-myers-squibb , University-of-kansas-medical-center , Department-of-rheumatology

Lupus Mutation May Unlock Targeted Drugs for Patient Subset

A new study provides definitive proof of one pathway that contributes to lupus, though it’s unclear how many patients with lupus are affected by this mechanism.

New-york , United-states , Australia , London , City-of , United-kingdom , Canberra , Australian-capital-territory , Australian , Ignacio-sanz , Laura-lewandowski , Carolag-vinuesa

EULAR Congress Opens New Avenues for Learning, Collaborating

New and slightly altered session formats break new ground in the first-time hybrid congress, taking place June 1-4 in Copenhagen, Denmark, and virtually.

Germany , Italy , Copenhagen , Køavn- , Denmark , Munich , Bayern , Marta-mosca , Hendrik-schulze-koops , European-alliance-of-associations , University-of-pisa , Ludwig-maximilian-university-of-munich

EULAR CVD Management Guidance Focuses on Gout, Lupus, Vasculitis

The recommendations advise on managing cardiovascular health in patients with gout, vasculitis, systemic sclerosis, myositis, Sjögren syndrome, lupus, antiphospholipid syndrome, and other diseases.

Minnesota , United-states , Athens , Attikír , Greece , Mayo-clinic-in-rochester , American , Georgec-drosos , Duarte-garcia , Alia-duarte-garcia , Christiem-bartels , University-of-wisconsin

What's New in Sjögren Disease: Update From ACR 2021

Three experts in Sjögren disease describe some of the most interesting and influential abstracts that were presented at the American College of Rheumatology's 2021 Annual Meeting.

Oklahoma , United-states , Japan , Netherlands , Maurik , Gelderland , Groningen , Greece , American , Oklahoma-medical-research-foundation , University-medical-center-groningen

Small Fiber Neuropathy Rising in the US, But Why Is a Mystery

Over the past two decades there has been a significant increase in the number of adults in the United States with small fiber neuropathy, but in many cases, no cause can be determined.

Minnesota , United-states , Mayo-clinic-in-rochester , Ann-arbor , Michigan , Salt-lake-city , Utah , University-of-utah , J-robinson-singleton , Brian-callaghan , Christopherj-klein , Important-research