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A new genetic model takes into account data from people across diverse ancestries. The polygenic model, developed at MIT, dramatically increased accuracy of predictions for many traits, especially for people from previously underrepresented populations.
Alzheimer's disease affects more than 6 million people in the United States, and there are very few FDA-approved treatments that can slow the progression of the disease.
Using more than 2 million cells from over 400 postmortem brain samples, MIT researchers performed the largest-scale analysis of the genomic, epigenomic, and transcriptomic changes that occur in every cell type in the brains of Alzheimer’s patients.
People with an abundance of specific neurons are more likely to escape cognitive decline despite having signs of Alzheimer’s in their brains. People with an abundance of specific neurons are more likely to escape cognitive decline despite having signs of Alzheimer’s in their brains.
Innovating at the intersection of chemistry, biology, and engineering, Professor Brad Pentelute and the MIT Pentelute Laboratory are revolutionizing