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Study shows how certain cancers neutralize T cells to subvert immune system and help tumors grow

Study shows how certain cancers neutralize T cells to subvert immune system and help tumors grow
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Dana-farber-cancer-institute , Massachusetts , United-states , Gregory-baker , Jefte-drijvers , Arlene-sharpe , Heide-baron , Alison-ringel , Bruker-daltonics , Jia-ren-lin , Nathalie-agar , Gerard-baquer

Disarming body's defenders | Mirage News

Disarming body's defenders | Mirage News
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Dana-farber-cancer-institute , Massachusetts , United-states , Gregory-baker , Jefte-drijvers , Arlene-sharpe , Heide-baron , Alison-ringel , Bruker-daltonics , Jia-ren-lin , Nathalie-agar , Gerard-baquer

Researchers discover how cancer cells can turn off the immune system to help tumors grow

When cancer arises in the body, it starts with tumor cells that rapidly grow and divide and eventually spread.

Marcia-haigis , Giulia-notarangelo , Emily-henderson , Harvard-medical-school , Blavatnik-institute , Senior-author , Cell-biology , Genomics-industry-focus , Cell-metabolism , Cancer , Ell , Ell-metabolism

Allison Institute announces formation of scientific advisory board

Allison Institute announces formation of scientific advisory board
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

New-york , United-states , Australia , United-kingdom , Missouri , Texas , Ohio-state-university , Ohio , Boston , Massachusetts , Melbourne , Victoria

Biochemistry Colloquium: Marcia Haigis | UW–Madison Events Calendar

Biochemistry Colloquium: Marcia Haigis | UW–Madison Events Calendar
wisc.edu - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from wisc.edu Daily Mail and Mail on Sunday newspapers.

Marcia-haigis , Biochemistry-colloquium ,

OPINION: Letter to the editor

Local medical professionals support COVID-19 pooled testing
We are a multidisciplinary group of local physicians, scientists, nurses and pediatric specialists who have come together to help support the community.
We are pleased that the state is offering public schools a program to support six weeks of pooled surveillance testing for COVID-19 and that Winchester Public Schools is planning to participate, starting with Winchester High School. We’d like to applaud the School Committee and the Board of Health for supporting this. The Select Board has committed to help fund this effort during the initial six weeks and potentially beyond, and we are grateful that they recognize the public health importance of testing.

Andover , Massachusetts , United-states , Boston , Mount-auburn-hospital , Winchester-high-school , Boston-university , Winchester-hospital , Winston-churchill , Jennifer-hensley , Shannon-reynolds , Taylor-horst

Does Obesity Affect Immunity?

Jan 27 2021 Read 23357 Times
New research from Harvard Medical School warns obesity could impair the function of immune cells and potentially accelerate tumour growth. Citing competition for fuel as a key driver, scientists warn a high-fat diet could allow cancer cells to outperform immune cells and spread within the body. The study builds on existing research suggesting links between obesity and more than a dozen different types of cancer, with scientists previously exploring drivers such as chronic inflammation and metabolic changes.
Working from Harvard Medical School, the team conducted studies on mice to uncover new insight into the relationship between obesity and cancer. The results could spark exciting change for cancer immunotherapy, with the team noting obesity allows malignant cells to outperform a critical type of tumour-killing immune cell known as CD8+ T. Used in many different types of immunotherapies, CD8+ T kickstart the immune system and play a critical role in defencing cells against intracellular pathogens.

Marcia-haigis , Arlene-sharpe , Louise-bonnemay , Marie-charlotte-manus , Blavatnik-institute-at-harvard-medical-school , Harvard-medical-school , Blavatnik-institute , Harvard-medical , Matthieu-opitz , மார்சியா-ஹைகிஸ் , அர்லேனே-கூர்மையான , மேரி-சார்லோட்-மனுச்

A cancer link to obesity: A metabolic tug-of-war - INDIA New England News

A cancer link to obesity: A metabolic tug-of-war
The Harvard Gazette
Obesity has been linked to increased risk for over a dozen different types of cancer, as well as worse prognosis and survival. Over the years, scientists have identified obesity-related processes that drive tumor growth, such as metabolic changes and chronic inflammation, but a detailed understanding of the interplay between obesity and cancer has remained elusive.
Now, in a study in mice, Harvard Medical School (HMS) researchers have uncovered a new piece of this puzzle, with surprising implications for cancer immunotherapy: Obesity allows cancer cells to outcompete tumor-killing immune cells in a battle for fuel.

Cong-hui-yao , Vikram-juneja , Gregory-baker , Arlene-sharpe , Jefte-drijvers , Alison-ringel , Thao-nguyen , Marcia-haigis , Steven-gygi , Haejin-yoon , Justin-trombley , Juan-garc

Obesity Impairs Immune Cell Function in Cancer, Triggers Tug-of-War for Fuel

Obesity Impairs Immune Cell Function in Cancer, Triggers Tug-of-War for Fuel
December 10, 2020
Source: Science Artwork/Science Photo Library/Getty Images
Research by a Harvard Medical School (HMS)-led research team has uncovered a new mechanism by which obesity can interfere with the immune system’s ability to fight cancer. Their studies demonstrated how, in tumor-bearing mice fed a high-fat diet, cancer cells reprogram their metabolism in response to the increased fat availability, so they can better consume energy-rich fat molecules, which then deprives tumor-killing T cells of fuel and accelerates tumor growth. The cancer cells effectively outcompete the immune cells in the battle for fuel, leading to reduced numbers and activity of CD8+ T cells in the tumor microenvironment (TME). Because CD8+ T cells are the main weapon used by immunotherapies that activate the immune system against cancer, the study results could point to potential new strategies for improving these treatment approaches.

United-states , Marcia-haigis , Arlene-sharpe , Jefte-drijvers , Alison-ringel , George-fabyan , Harvard-medical-school , Science-artwork-photo-library-getty-images , Blavatnik-institute , Science-photo , Shapes-metabolism , Tumor-microenvironment

Harvard study shows how obesity can boost cancer growth

Harvard study shows how obesity can boost cancer growth
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Marcia-haigis , Harvard-medical-school , Harvard-medical , மார்சியா-ஹைகிஸ் , ஹார்வர்ட்-மருத்துவ-பள்ளி , ஹார்வர்ட்-மருத்துவ ,