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By Bill Snyder Researchers at Vanderbilt University Medical Center and the University of Texas Medical Branch (UTMB) at Galveston have discovered what...

Viral ExoN regulates the rate of recombination in SARS-CoV-2 Researchers at Vanderbilt University Medical Center (VUMC) and the University of Texas Medical Branch (UTMB) at Galveston have discovered what may be the Achilles' heel of the coronavirus, a finding that may help close the door on COVID-19 and possibly head off future pandemics. The coronavirus is an RNA virus that has, in its enzymatic toolkit, a "proofreading" exoribonuclease, called nsp14-ExoN, which can correct errors in the RNA sequence that occur during replication, when copies of the virus are generated. Using cutting-edge te...

 E-Mail IMAGE: Jennifer Gribble, a graduate student in the laboratory of Mark Denison, MD, at Vanderbilt University Medical Center. view more  Credit: Vanderbilt University Medical Center Researchers at Vanderbilt University Medical Center (VUMC) and the University of Texas Medical Branch (UTMB) at Galveston have discovered what may be the Achilles' heel of the coronavirus, a finding that may help close the door on COVID-19 and possibly head off future pandemics. The coronavirus is an RNA virus that has, in its enzymatic toolkit, a "proofreading" exoribonuclease, called nsp14-ExoN, ...

NewsSportsEntertainmentLifestyleOpinionUSA TODAYObituariesE-EditionLegals 2020 Distinguished Kansans worked to help others in difficult year Rick Bright, Tonja Harrison, Meg Heriford, Mark Denison, Noah Lindquist, Dennis Ruhnke, Jimmie Pottberg, Theresa Gee, Amy Schremmer and Teresa Walters are 2020 Distinguished Kansans for their efforts. Topeka Capital-Journal Hutchinson native Rick Bright was director of the Biomedical Advanced Research and Development Authority, the federal agency involved in developing novel coronavirus vaccines, drugs, and tests, when demoted in April for raising conce...

How Changing the Definition of Pandemic Altered Our World Mid-March 2020 predictions said COVID-19 would kill 2.2 million Americans if allowed to run its course. 1 By the end of March, Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, downgraded the projected death toll, saying we were probably looking at 100,000 to 240,000 Americans dying. 2 April 8, 2020, a new model referred to as the Murray Model 3 downgraded the threat further, predicting COVID-19 will kill 60,000 in the U.S. by August 2020 4 — a number that is still 20,000 lower than the Cent...