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Novel therapeutic approach identified for overcoming resistance in B-cell leukemia

Despite having an overall survival rate of 94%, B-cell acute lymphoblastic leukemia (B-ALL), the most common childhood cancer, can prove challenging to treat, with survival among relapsed or resistant cases falling between 30-50%.

Texas , United-states , Xin-huang , Zhejiang , China , Peking , Beijing , Xu-yang , Shaanxi , Charles-mullighan , Seth-karol , Steven-kornblau

Novel Drug Combo Targets B-cell Vulnerability to Treat Leukemia

Novel Drug Combo Targets B-cell Vulnerability to Treat Leukemia
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Xu-yang , Shaanxi , China , Texas , United-states , Peking , Beijing , Xin-huang , Zhejiang , Jingliao-zhang , William-evans , Elias-jabbour

Targeting vulnerability in B-cell development leads to novel drug combination for leukemia

Targeting vulnerability in B-cell development leads to novel drug combination for leukemia
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Xu-yang , Shaanxi , China , Peking , Beijing , Xin-huang , Zhejiang , Texas , United-states , Mark-litzow , Huanbin-zhao , Satoshi-yoshimura

Targeting vulnerability in B-cell development leads to novel drug combination for leukemia

Targeting vulnerability in B-cell development leads to novel drug combination for leukemia
newswise.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from newswise.com Daily Mail and Mail on Sunday newspapers.

Xu-yang , Shaanxi , China , Texas , United-states , Xin-huang , Zhejiang , Peking , Beijing , Seth-karol , William-evans , Wenjian-yang

Combination of dasatinib and blinatumomab offers effective treatment for older Ph+ ALL patients

Older patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) who were not good candidates for the standard treatment of intensive chemotherapy had a median overall survival (OS) of 6.5 years on an alternate regimen of dasatinib and blinatumomab.

Philadelphia , Pennsylvania , United-states , American , Brentl-wood , Susanm-obrien , Anjalis-advani , Aaront-gerds , Jeraldp-radich , Mark-litzow , Janel-liesveld , Matthew-wieduwilt

Combo Treatment Sans Chemotherapy Effective for Ph+ ALL Elderly

Combo Treatment Sans Chemotherapy Effective for Ph+ ALL Elderly
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

United-states , Philadelphia , Pennsylvania , American , Mark-litzow , Matthew-wieduwilt , Ceciliacs-yeung , Ehabl-atallah , Anna-moseley , Susanm-obrien , Aaront-gerds , Megan-othus

Blinatumomab-Chemo Consolidation a 'New Standard' in MRD-Negative B-ALL

Phase III study showed 58% reduction in the risk of death versus chemo alone

Minnesota , United-states , Mayo-clinic-in-rochester , Canada , Israel , Massachusetts , American , Mark-litzow , Cynthia-dunbar , Mike-bassett , American-society-of-hematology , National-heart

Blinatumomab further improves survival among B-lineage ALL patients with a good prognosis

Study in ASH Late-Breaking Abstracts session: Blinatumomab further improves survival among B-lineage ALL patients with a good prognosis.

Israel , Minnesota , United-states , Mayo-clinic-in-rochester , Canada , American , Mark-litzow , Development-agreement , Amgen , National-clinical-trials-network , National-cancer-institute , National-institutes-of-health