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PET brain scans could reveal hidden inflammation in patients with multiple sclerosis

A Brigham and Women’s Hospital study of 30 people found that, in patients with MS, advanced brain imaging could identify hidden inflammation not picked up on traditional MRIs

Tarun-singhal , Rohit-bakshi , Clinical-nuclear-medicine , Ann-romney-center , Imaging-program , Brigham-multiple-sclerosis-center , Department-of-neurology , Mass-general-brigham , Clinical-nuclear , Ann-romney , Brain , Nflammation

Blood test rivals spinal fluid analysis in Alzheimer's detection

A study reveals blood test %p-tau217 matches or surpasses CSF tests in detecting Alzheimer's disease pathology, offering a less invasive, equally accurate alternative for diagnosis across various stages.

Sweden , United-states , Swedish , Juan-gaertner , Drug-administration , Knight-alzheimer-disease-research-center , Nature-medicine , Highly-accurate-blood-test , Disease-comparable , Image-credit , Blood , Lood-test

What are the capabilities of a commercially available p-tau217 immunoassay to identify Alzheimer disease pathophysiology?

Researchers determined the utility of a novel and commercially available immunoassay for plasma phosphorylated tau 217 to detect Alzheimer's Disease pathology and evaluate reference ranges for abnormal amyloid β and longitudinal change across three selected cohorts.

Wisconsin , United-states , Roche-neurotoolkit , Sant-pau-initiative-on-neurodegeneration , Translational-biomarkers , Wisconsin-registry , Sant-pau-initiative , Immunoassay , Athophysiology , Lzheimer-39s-disease , Iomarker , Lood

This 3D-printed 'body-on-chip' can save animals from drug tests

A team of scientists at the University of Edinburgh, UK has developed a ground-breaking 3D-printed "body-on-chip" that mimics the effect of medicines on a human body, according to media report Thursday December 28, 2023.

United-kingdom , Edinburgh , City-of , London , Susan-bodie , University-of-edinburgh , Unilever , National-centre-for-replacement , Thursday-december , Positron-emission-tomography , Liam-carr , National-centre

Curium Announces First Patients in Europe Injected With PYLCLARI® – an Innovative 18F-PSMA Pet Tracer Indicated in Patients With Prostate Cancer

PARIS, Nov. 16, 2023 (GLOBE NEWSWIRE) -- Curium, a world leader in nuclear medicine, announced today that in partnership with its exclusive distributor SYN Innovation Laboratories in Greece, the first patients in Greece have been injected with PYLCLARI® (INN: Piflufolastat (18F) also known as (18 F)-DCFPyL, indicated for the detection of prostate-specific membrane antigen (PSMA) positive lesions with positron emission tomography (PET) in patients with prostate cancer in the following clinical se

United-states , Paris , France-general- , France , Athens , Attikír , Greece , Benoit-woessmer , Pierre-curie , Ross-bethell , Savvas-thalasselis , European-union

Surveillance Imaging After Head, Neck Cancer Remission?

With no apparent benefit for most, investigators say routine surveillance imaging in asymptomatic patients with head and neck cancer "should be discouraged."

Irvine , California , United-states , Allen-chen , University-of-california , Malignant-head-and-neck-neoplasm , Otolaryngology , Nt-ears , Ose , Hroat- , Cancer , Alignant-neoplasia

Neural circuits respond to rapid dopamine surges

Researchers assess the pharmacodynamics of dopamine signaling, brain connectivity/activity, and self-documented 'high' following methylphenidate exposure.v

Washington , United-states , Yuliia-shutterstock , Nature-communications , Pavlova-yuliia , Human-connectome-project , Dopamine , Ddiction , Rain , Ortex , Rug-delivery , Rugs

New radio-theranostics approach shows promise in the fight against pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers worldwide, with a 5-year survival rate of less than 10%. Many PDAC tumors in early stage go undetected because they are not found using conventional imaging methods, including fluorodeoxyglucose positron emission tomography (PET) scans.

Osaka , Japan , Tadashi-watabe , Lily-ramsey , Kazuya-kabayama , Osaka-university , Journal-of-nuclear-medicine , Nuclear-medicine , Adenocarcinoma , Ntibody , Ancer , Iagnostic