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Evaluating the anti-cancer efficacy of Chitosan nanoparticles loaded with hGH fragment 176–191 peptide plus the clinical chemotherapeutic doxorubicin. Read more

Researchers used the SARS-CoV-2 sequence against aptamers to perform the in silico selection of an aptamer against the SARS-CoV-2 S protein.

Cyanobacteria have evolved complicated mechanisms to transform light energy into chemical energy during three billion years of existence. Cyanobacteria produce reducing power (NADPH) and chemical energy (ATP) for carbon dioxide fixation using only the most basic of ingredients: light and water.

The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a pandemic due to the high transmission and mortality rate of this virus. The world health and economic sectors have been severely affected by this deadly virus, exacerbated by the lack of sufficient efficient vaccines. The design of effective drug candidates and their rapid development is necessary to combat this virus. In this study, we selected 23 antimicrobial peptides from the literature and predicted their structure using PEP-FOLD 3.5. In addition, we docked them to the SARS-CoV-2 spike protein receptor...

In a new study published in the journal Pathogens, researchers have summarized the role of the macrodomain in viral replication and virulence and further reviewed the development of macrodomain inhibitors as antiviral agents.