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Welcome to the 2 Minute Medicine Podcast, summarizing the latest medical studies, curated and written by practicing physicians. On this podcast, twice a month, we cover the latest in healthcare news and research evidence. Our episode is live! Episode Description We begin this episode by discussing our article of the week from the New England
1. In this randomized controlled trial, ketamine was noninferior to electroconvulsive therapy (ECT) for reducing symptoms of treatment-resistant major depression (TRMD). 2. ECT was associated with temporarily decreased memory recall and musculoskeletal adverse effects, while ketamine was associated with dissociation. Evidence Rating Level: 1 (Excellent) Study Rundown: Major depressive disorder is a leading cause of
The results show 55.4% of patients in the ketamine group had a response, compared to 41.2% of patients in the ECT group.
For patients with treatment-resistant major depression without psychosis, ketamine is noninferior to electroconvulsive therapy.
For patients with treatment-resistant major depression without psychosis, ketamine is noninferior to electroconvulsive therapy.