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India's Covaxin vaccine likely effective against UK SARS-CoV-2 variant: Study


India s Covaxin vaccine likely effective against UK SARS-CoV-2 variant: Study
The worldwide increase in the circulation of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to the crossing of the shocking milestone of 100 million reported cases.  Among the chief causes of growth in infection numbers have been the emergence of new variants, notably the UK variant, with increased infectivity relative to the ancestral strain. However, a new preprint research paper, posted to the preprint server
bioRxiv , presents data indicating that the Indian-made Covaxin vaccine candidate successfully neutralizes this variant, preventing infection when challenged by it.
The UK variant
The UK variant is also called the Variant of Concern (VOC) 202012/01, also known as lineage B.1.1.7 or 20B/501Y.V1. It has rapidly increased as a proportion of new cases of COVID-19 in the UK in the space of fewer than two months. B.1.1.7  has been sequenced from other countr ....

United Kingdom , South Africa , South African , Oxford Astrazeneca , Liji Thomas , Indian Made Covaxin , United Kingdom Returnees , Indian Manufactured Oxford Astra Zeneca , Sars Cov 2 , Corona Virus , Coronavirus Disease Covid 19 , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , ஒன்றுபட்டது கிஂக்டம் , இந்தியன் தயாரிக்கப்பட்டது ஆக்ஸ்ஃபர்ட் அஸ்ட்ரா ஸெநெக , கொரோனா வைரஸ் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,

Synergistic effect between NF-κB inhibitors and zinc in vitro reducing ACE2 expression


Synergistic effect between NF-κB inhibitors and zinc in vitro reducing ACE2 expression
Researchers at National Taiwan University Hospital in Taipei have conducted a study demonstrating the potential effectiveness of a novel drug combination at reducing morbidity and mortality in coronavirus disease 2019 (COVID-19).
In a study using two human cell lines, a combination of the clinical drugs triclabendazole and emetine effectively suppressed expression of the host cell receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).
Furthermore, this suppressive effect was enhanced by the addition of zinc sulfate, suggesting that zinc supplementation might further increase the potential clinical application of the drug combination for COVID-19 prevention and treatment. ....

National Taiwan University Hospital , T Ai Pei , Sally Robertson , Researchers At National Taiwan University Hospital , Drug Administration , Bor Ru Lin , In Vitro , Corona Virus , Coronavirus Disease Covid 19 , Sars Cov 2 , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , Signaling Pathway , Spike Protein , Zinc Sulfate , தேசிய டைவாந் பல்கலைக்கழகம் மருத்துவமனை , டி ஐ பேய் , சாலி ராபர்ட்சன் , ஆராய்ச்சியாளர்கள் இல் தேசிய டைவாந் பல்கலைக்கழகம் மருத்துவமனை , போர் ரு லின் , இல் விட்ரோ , கொரோனா வைரஸ் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி , சமிக்ஞை நடைபாதை , ஸ்பைக் ப்ரோடீந் ,

Startup develops yeast-based test to detect the presence of SARS-CoV-2 in saliva


Startup develops yeast-based test to detect the presence of SARS-CoV-2 in saliva
Incubated at the University of Campinas (UNICAMP) in the state of São Paulo, Brazil, and supported by São Paulo Research Foundation- FAPESP s Innovative Research in Small Business Program (PIPE), BIOinFOOD is a startup that is developing a rapid COVID-19 diagnostic test based on a patent application filed by students at UNICAMP s Genomics and Bioenergy Laboratory.
The test is based on a biosensor consisting of a genetically modified brewer s yeast (Saccharomyces cerevisiae), which changes color if human ACE2 receptor expressed by the yeast s membrane binds to the spike glycoprotein present on the external surface of the virus. ....

Amarante Guimar , Gleidson Silva Teixeira , Emily Henderson , Paulo Research , Innovative Research In Small Business Program , Institute Of Biology , Bioenergy Laboratory , University Of Campinas , Small Business Program , Silva Teixeira , Professor Gon , Corona Virus , Saccharomyces Cerevisiae , Sars Cov 2 , கிலேட்சொன் சில்வா டெக்ஸ்ர , எமிலி ஹென்டர்சன் , பாலொ ஆராய்ச்சி , புதுமையானது ஆராய்ச்சி இல் சிறிய வணிக ப்ரோக்ர்யாம் , நிறுவனம் ஆஃப் உயிரியல் , உயிர்வேதியியல் ஆய்வகம் , பல்கலைக்கழகம் ஆஃப் காம்பினாக்கள் , சிறிய வணிக ப்ரோக்ர்யாம் , சில்வா டெக்ஸ்ர , ப்ரொஃபெஸர் கோன் , கொரோனா வைரஸ் , சர்வதேச பரவல் ,

Chinese spice provides insight into how human brains detect and perceive touch


Chinese spice provides insight into how human brains detect and perceive touch
New insight into how human brains detect and perceive different types of touch, such as fluttery vibrations and steady pressures, has been revealed by UCL scientists with the help of the ancient Chinese cooking ingredient, Szechuan pepper.
Humans have many different types of receptor cells in the skin that allow us to perceive different types of touch. For more than a century, scientists have puzzled over whether touch signals from each type of receptor are processed independently by the brain, or whether these different signals interact before reaching conscious perception. ....

Emily Henderson , Proceedings Of The Royal Society , Institute Of Cognitive Neuroscience , Patrick Haggard , Lead Author , எமிலி ஹென்டர்சன் , நிறுவனம் ஆஃப் அறிவாற்றல் நரம்பியல் , பேட்ரிக் ஹாகார்ட் , வழி நடத்து நூலாசிரியர் ,