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Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1 - Vimarsana News

Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1

Phosphatidylcholine and phosphatidylethanolamine, the two most abundant phospholipids in mammalian cells, are synthesized de novo by the Kennedy pathway from choline and ethanolamine, respectively1–6. Despite the essential roles of these lipids, the mechanisms that enable the cellular uptake of choline and ethanolamine remain unknown. Here we show that the protein encoded by FLVCR1, whose mutation leads to the neurodegenerative syndrome posterior column ataxia and retinitis pigmentosa7–9, transports extracellular choline and ethanolamine into cells for phosphorylation by downstream...

Source: nature.com
Unveiling the World's Largest Digital Camera for Researching Elusive Dark Matter and Dark Energy - Vimarsana News

Unveiling the World's Largest Digital Camera for Researching Elusive Dark Matter and Dark Energy

Unveiling the World's Largest Digital Camera for Researching Elusive Dark Matter and Dark Energy - Industry Tap

Unlocking the Power of Quick and Engaging Instagram and Pinterest Posts - Vimarsana News

Unlocking the Power of Quick and Engaging Instagram and Pinterest Posts

Social media efforts that fall short of your desired engagement levels can be avoided; mastering the art of quick and engaging Instagram and Pinterest posts is a game-changer in today’s world of fleeting attention spans. How can you transform your social media presence from a mere existence to a dynamic force that commands attention?You’ll learn […]

Quitter's Day is coming (not another "Great Resignation" - Vimarsana News

Quitter's Day is coming (not another "Great Resignation"

How to make AND keep New Year's Resolutions with Beth Handel on ABC...

Electron cryo-microscopy sheds light on how bioenergy makers are made in our body - Vimarsana News

Electron cryo-microscopy sheds light on how bioenergy makers are made in our body

 E-Mail IMAGE: Mitoribosomes are tethered to the mitochondrial inner membrane to facilitate insertion of synthesized proteins (yellow) encoded by the mitochondrial genome. A gating mechanism of the exit tunnel (cyan) enables protein... view more  Credit: Dan W. Nowakowski and Alexey Amunts Mitochondria are organelles that act as the powerhouses in our body. They use oxygen which we inhale and food we eat to produce energy that supports our life. This molecular activity is performed by bioenergetic nano-factories incorporated in specialized mitochondrial membranes. The nano-factories...