Lipid Res News Today : Breaking News, Live Updates & Top Stories | Vimarsana

Phosphatidylcholine and phosphatidylethanolamine, the two most abundant phospholipids in mammalian cells, are synthesized de novo by the Kennedy pathway from choline and ethanolamine, respectively1–6. Despite the essential roles of these lipids, the mechanisms that enable the cellular uptake of choline and ethanolamine remain unknown. Here we show that the protein encoded by FLVCR1, whose mutation leads to the neurodegenerative syndrome posterior column ataxia and retinitis pigmentosa7–9, transports extracellular choline and ethanolamine into cells for phosphorylation by downstream...

Embryo-derived tissue-resident macrophages are the first representatives of the haematopoietic lineage to emerge in metazoans. In mammals, resident macrophages originate from early yolk sac progenitors and are specified into tissue-specific subsets during organogenesis—establishing stable spatial and functional relationships with specialized tissue cells—and persist in adults. Resident macrophages are an integral part of tissues together with specialized cells: for instance, microglia reside with neurons in brain, osteoclasts reside with osteoblasts in bone, and fat-associated macr...

In the final instalment of the Cholesterol Con series, Noakes concludes the account of the greatest scam in the history of modern medicine.

Noakes continues Keys' cholesterol con in 1993 with the invention of the Mediterranean Diet by Harvard's Professor Walter Willett, MD.

Perhaps the most shocking article in the Cholesterol Con series, Part Twelve details the depths of institutional collusion and corruption.