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WPVI Action News July 8, 2014 - Vimarsana News

WPVI Action News July 8, 2014

Police in buck county search for the gunman in a triple shoot that left one dead. And eating healthy, seniors get help getting fresh fruits and vegetables. But the big story is the big fire that killed four children in southwest philadelphia. Demonstrators were outside of the firehouse around the corner from the deadly blaze, they believe that firefighters took too long to respond. John rawlins, joins us live from the firehouse in southwest philadelphia with more on what is happening today. Reporter hi sara, all is quiet right now, ladder 4 was dispatched six or seven minutes ago. Quite a comm...

EGF receptor-targeting cancer therapy using CD47 - Vimarsana News

EGF receptor-targeting cancer therapy using CD47

Evaluating the nanoparticles expressing CD47 proteins inhibiting the phagocytic attack of immune cells and as an anti-cancer drug delivery vehicle

IGF-1 Facilitates Cartilage Reconstruction by Regulating PI3K/AKT, MAP - Vimarsana News

IGF-1 Facilitates Cartilage Reconstruction by Regulating PI3K/AKT, MAP

Conclusion In conclusion, we established the healing effects of IGF-1 in chondrocytes and a rabbit model against osteoarthritis. IGF-1 inhibited the NF-κB, p38 (MAPK), and PI3K/AKT signaling pathways, thereby preventing MMPs expression during OA pathogen, and also balanced collagen type II and proteoglycan and formation of hyaline cartilage. Therefore, in articular cartilage lesions, Intra-articular injection of IGF-1 leading a better tactic for effective and efficient therapy. So, our study revealed that IGF-1 could be a potential therapeutic mediator for the management of cartilage damage ...