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Experts review new studies on cardiovascular effects of cigarette smoking versus electronic cigarettes

Electronic cigarette (EC) use, or vaping, has both gained incredible popularity and generated tremendous controversy, but although they may be less harmful than tobacco cigarettes (TCs), they have major potential risks that may be underestimated by health authorities, the public, and medical professionals. ....

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Update on DARE-19 Phase III trial for Farxiga in COVID-19

Date Time
Update on DARE-19 Phase III trial for Farxiga in COVID-19
AstraZeneca and Saint Luke’s Mid America Heart Institute today announced high-level results of the primary analysis from the DARE-19 Phase III trial assessing the potential of Farxiga (dapagliflozin) to treat patients hospitalised with COVID-19 who are at risk of developing serious complications.
The trial did not achieve statistical significance for the primary endpoint of prevention measuring organ dysfunction and all-cause mortality, and the primary endpoint of recovery measuring a change in clinical status (from early recovery to death), at 30 days.
DARE-19 was the first Phase III trial to evaluate the safety and efficacy of a sodium-glucose co-transporter-2 (SGLT2) inhibitor in patients hospitalised with COVID-19 who also have risk factors for developing serious complications, including hypertension (HTN), type-2 diabetes (T2D), atherosclerotic cardiovascular disease (ASCVD), heart failure ( ....

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CPR training offered to just over half of surveyed ON high school students despite mandated training

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Just over half of surveyed Ontario high schools reported providing CPR and AED training to students despite being mandated by the province to provide training for the lifesaving technique, according to a new study by Unity Health Toronto researchers.
The study, published Monday April 12, in
CJC Open, surveyed elementary and high schools from 15 different school boards across Ontario to understand the scope of Cardiopulmonary Resuscitation (CPR) and Automated External Defibrillator (AED) training, which are mandated in the Ontario Grade 9 Health and Physical Education Curriculum. Researchers from St. Michael s Hospital of Unity Health Toronto worked with 120 elementary, 25 middle and 60 high schools to complete a web-based survey to understand the scope of this training. ....

Katherine Allan , Unity Health Toronto , Michael Hospital Of Unity Health Toronto , Monday April , Cardiopulmonary Resuscitation , Automated External Defibrillator , Ontario Grade , Physical Education , K 12 , Medicine Health , Public Health , Social Behavioral Science , க்யாதரிந் ஆலன் , ஒற்றுமை ஆரோக்கியம் டொராண்டோ , மைக்கேல் மருத்துவமனை ஆஃப் ஒற்றுமை ஆரோக்கியம் டொராண்டோ , திங்கட்கிழமை ஏப்ரல் , இருதய நுரையீரல் புத்துயிர் , தானியங்கி வெளிப்புறம் டேபைபிரில்லாதோர் , ஆஂடேரியொ தரம் , உடல் கல்வி , மருந்து ஆரோக்கியம் , பொது ஆரோக்கியம் , சமூக நடத்தை அறிவியல் ,

NIH training grant enhances opportunities for biomedical graduate students at AU

Credit: Kim Ratliff, Augusta University
Augusta University has received a $1.5 million grant from the National Institutes of Health to help support the graduate education of future scientists whose focus is cardiometabolic diseases like hypertension and diabetes which disproportionally affect minorities.
The training grant (1HL155011-01A1) will support four graduate students in its first year, and scale up to six students per year by year four of the five-year grant. It will offer aspiring PhDs and MD/PhDs the opportunity to learn from 43 federally funded scientists focusing on different aspects of cardometabolic disease related to minority health. Student recruitment has just started. ....

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New research on good cholesterol possibly finds better marker for cardiovascular disease

Credit: Ulf Sirborn
Good cholesterol, which is transported in HDLs (high-density lipoproteins), plays a key part in the prevention of atherosclerosis and thus the risk of cardiovascular disease. However, according to a new paper co-authored by researchers at Karolinska Institutet in Sweden and published in the journal
Circulation, the anti-inflammatory properties of HDLs could be an even better biomarker for future cardiovascular events.
Atherosclerosis is considered a chronic local inflammation that leads to plaques in the blood vessels and that, if left untreated, can cause cardiovascular disease, the most common cause of death in the world.
The inflammation, while unnoticeable, can cause considerable damage to the blood vessels, so it is important to identify at-risk individuals as early as possible to curb progression of the disease. ....

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