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Magnesium ions injected directly into compromised bone accelerate bone regeneration


Credit: The authors
Bone-regenerating treatments are in high demand due to the ageing population. Increasingly, the orthopaedic biomaterials used to support these treatments are designed to be immunomodulatory , i.e., guide the body s inflammatory response. They do this by encouraging macrophages - a type of white blood cell that surrounds and kills microorganisms - to adopt new roles based on signals and stimuli in their microenvironment. This approach has proved effective for developing new bone and for encouraging existing bone to accept artificial implants.
Magnesium is a mineral that not only helps to maintain normal nerve and muscle function, importantly, it also supports a healthy immune system and helps bones to retain their strength. Typically, it is given to orthopaedic patients as an oral supplement. ....

Hong Kong , University Of Hong Kong , Hong Kong General , Kelvin Yeung , Kelvin Wk Yeung , Zhengjie Lin , China Science Publishing Media Ltd , National Natural Science Foundation Of China , Bioactive Materials , China Science Publishing , Media Ltd , National Natural Science Foundation , Biomedical Environmental Chemical Engineering , ஹாங் காங் , பல்கலைக்கழகம் ஆஃப் ஹாங் காங் , ஹாங் காங் ஜநரல் , கெல்‌விந் யியுங் , சீனா அறிவியல் வெளியீடு மீடியா லிமிடெட் , தேசிய இயற்கை அறிவியல் அடித்தளம் ஆஃப் சீனா , சீனா அறிவியல் வெளியீடு , மீடியா லிமிடெட் , தேசிய இயற்கை அறிவியல் அடித்தளம் ,

Biological E, Providence Therapeutics tie up for mRNA vaccine, to run trials in India, seek EUA


Biological E, Providence Therapeutics tie up for mRNA vaccine, to run trials in India, seek EUA
June 01, 2021
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Targets 1 billion doses in 2022; Providence to supply 30 million doses from North American capacity
Canadian biotechnology company Providence Therapeutics Holdings Inc and the Hyderabad-based Biological E Ltd have signed up for a licensing and collaboration agreement for Providence’s mRNA vaccine, PTX-Covid19-B.
Providence will provide the technology transfer for Biological E to manufacture mRNA vaccines in India, with a minimum production capacity of 600 million doses in 2022 and a target capacity of 1 billion doses.
The agreement provides for sale of Providence’s 30 million doses of its proprietary mRNA vaccine to Biological E and other end-buyers. ....

Province Of Manitoba , Brad Sorenson , Mahima Datla , E Ltd , Providence Therapeutics Holdings Inc , Hyderabad Based Biologicale Ltd , Managing Director , Providence Therapeutics , Covid 19 , மாகாணம் ஆஃப் ம்யாநிடோப , பிராட் சோரன்சன் , மஹிமா டட்லா , ஏ லிமிடெட் , ப்ராவிடெந்ஸ் சிகிச்சை ஹோல்டிங்ஸ் இன்க் , நிர்வகித்தல் இயக்குனர் , ப்ராவிடெந்ஸ் சிகிச்சை ,

Gene plays major role in brain development


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IMAGE: Fluorescence image of two zebrafish embryos - After switching off the Plexin-A1 gene (bottom), malformations of the nervous system occur, such as a pathological enlargement of the neural fluid spaces.
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Credit: Dr. Gabriel Dworschak / University of Bonn
When the Augustinian monk Gregor Mendel crossed white-flowering with purple-flowering pea plants in the mid-19th century, he made an interesting discovery: The offspring were all purple. He therefore called this trait dominant, while the white blossom color was recessive. The reason for this phenomenon: In peas, each gene occurs twice. One version comes from the maternal plant and the other from the paternal plant. If a pea has inherited the gene for purple flower color from one parent, but the gene for white flower color from the other, purple wins. Only when two genes for white flowers come together in the offspring plant is it white. ....

United States , United Kingdom , Saudi Arabia , Baylor College Of Medicine , Nordrhein Westfalen , Benjamin Odermatt , Heiko Reutter , Gabrielc Dworschak , Gabriel Dworschak , Gregor Mendel , Jaya Punetha , University Of Bonn , Institute Of Anatomy , Institute Of Human Genetics , University Children Hospital , University Hospital Bonn , University Children , University Hospital , Human Genetics , Baylor College , Medicine Health , Developmental Reproductive Biology , ஒன்றுபட்டது மாநிலங்களில் , ஒன்றுபட்டது கிஂக்டம் , சவுதி அரேபியா , பேலர் கல்லூரி ஆஃப் மருந்து ,