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The FINANCIAL - Have a Case of a Covid Variant? No One Is Going to Tell You

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Covid-19 infections from variant strains are quickly spreading across the U.S., but there’s one big problem: Lab officials say they can’t tell patients or their doctors whether someone has been infected by a variant.
Federal rules around who can be told about the variant cases are so confusing that public health officials may merely know the county where a case has emerged but can’t do the kind of investigation and deliver the notifications needed to slow the spread, according to Janet Hamilton, executive director of the Council of State and Territorial Epidemiologists.
“It could be associated with a person in a high-risk congregate setting or it might not be, but without patient information, we don’t know what we don’t know,” Hamilton said. The group has asked federal officials to waive the rules. “Time is ticking.” ....

United States , University Of Washington , North Carolina , United Kingdom , South Africa , Carole Johnson , Joe Biden , Scott Becker , Nick Gilpin , Mark Pandori , Rochelle Walensky , Teresa Mccallion , Phil Febbo , Alex Greninger , Judy Kauerauf , Kaiser Permanente , Janet Hamilton , Centers For Disease , Us Centers For Medicare Medicaid Services , Henryj Kaiser Family Foundation , Drug Administration , Illinois Department Of Public Health , Nevada State Public Health Laboratory , Columbia University Brown Institute For Media Innovation , Clinical Laboratory Improvement Amendments , Kaiser Health News ,

Labs can't tell you if you have a COVID variant, a problem for tracking and prevention

Feb 26, 2021 11:55 AM EDT
COVID-19 infections from variant strains are quickly spreading across the U.S., but there’s one big problem: Lab officials say they can’t tell patients or their doctors whether someone has been infected by a variant.
Federal rules around who can be told about the variant cases are so confusing that public health officials may merely know the county where a case has emerged but can’t do the kind of investigation and deliver the notifications needed to slow the spread, according to Janet Hamilton, executive director of the Council of State and Territorial Epidemiologists.
“It could be associated with a person in a high-risk congregate setting or it might not be, but without patient information, we don’t know what we don’t know,” Hamilton said. The group has asked federal officials to waive the rules. “Time is ticking.” ....

United States , University Of Washington , North Carolina , United Kingdom , South Africa , Carole Johnson , Joe Biden , Scott Becker , Nick Gilpin , Mark Pandori , Rochelle Walensky , Teresa Mccallion , Phil Febbo , Alex Greninger , Judy Kauerauf , Janet Hamilton , Centers For Disease , Us Centers For Medicare Medicaid Services , Drug Administration , Illinois Department Of Public Health , Nevada State Public Health Laboratory , Columbia University Brown Institute For Media Innovation , Clinical Laboratory Improvement Amendments , Beaumont Health , Association Of Public Health Laboratories , Disease Control ,

Have a case of a COVID variant? No one is going to tell you

Feb 26, 2021 3:20pm
Tests for detecting variants have not yet been approved as a diagnostic either by the FDA or under federal rules governing university labs. (Getty Images)
COVID-19 infections from variant strains are quickly spreading across the U.S., but there’s one big problem: Lab officials say they can’t tell patients or their doctors whether someone has been infected by a variant.
Federal rules around who can be told about the variant cases are so confusing that public health officials may merely know the county where a case has emerged but can’t do the kind of investigation and deliver the notifications needed to slow the spread, according to Janet Hamilton, executive director of the Council of State and Territorial Epidemiologists. ....

University Of Washington , United States , North Carolina , South Africa , Carole Johnson , Joe Biden , Scott Becker , Nick Gilpin , Mark Pandori , Rochelle Walensky , Teresa Mccallion , Phil Febbo , Alex Greninger , Judy Kauerauf , Janet Hamilton , Centers For Disease , Us Centers For Medicare Medicaid Services , Drug Administration , Illinois Department Of Public Health , Nevada State Public Health Laboratory , Columbia University Brown Institute For Media Innovation , Clinical Laboratory Improvement Amendments , Beaumont Health , Association Of Public Health Laboratories , Translational Insights Key , Successful First In Human ,

Emerging Lessons From COVID-19 for the US Clinical Research Enterprise | Research, Methods, Statistics | JAMA

Perrine Janiaud, PhD; Cathrine Axfors, MD, PhD; Andreas M. Schmitt, MD; Viktoria Gloy, PhD; Fahim Ebrahimi, MD, MSc; Matthias Hepprich, MD; Emily R. Smith, ScD, MPH; Noah A. Haber, ScD; Nina Khanna, MD; David Moher, PhD; Steven N. Goodman, MD, PhD; John P. A. Ioannidis, MD, DSc; Lars G. Hemkens, MD, MPH
In this issue of
JAMA, Janiaud et al
1 present a meta-analysis of randomized clinical trials (RCTs) of convalescent plasma for the treatment of patients with COVID-19. Based on an analysis of 1060 patients from 4 RCTs published in peer-reviewed journals and 10 722 patients from 6 RCTs (5 published as preprints and 1 as a press release), the authors found that treatment with convalescent plasma vs placebo or standard of care was not associated with a significant decrease in all-cause mortality (risk ratio, 0.93 [95% CI, 0.63-1.38] for the 4 peer-reviewed RCTs; risk ratio, 1.02 [95% CI, 0.92-1.12] for all 10 RCTs) or with benefit for other cli ....

United Kingdom , Northern Ireland , Derekc Angus , Scaife Hall , Multifactorial Adaptive Platform Trial For Community , National Institutes Of Health , Biomedical Advanced Research , Drug Administration , Development Authority , National Health Service , Health Research Authority , National Institute For Health Research , Department Of Health , Urgent Public Health , Clinical Research Network , Clinical Research , Outcomes Research Institute , Us Centers For Medicare Medicaid Services , Emergency Use Authorization , Operation Warp Speed , National Institutes , Patient Centered Outcomes Research Institute , National Institute , Health Research , Randomized Evaluation , Multifactorial Adaptive Platform Trial ,

Have a case of a COVID-19 variant? No one is going to tell you

Have a case of a COVID-19 variant? No one is going to tell you
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United States , University Of Washington , North Carolina , United Kingdom , South Africa , Carole Johnson , Joe Biden , Scott Becker , Nick Gilpin , Mark Pandori , Rochelle Walensky , Teresa Mccallion , Phil Febbo , Alex Greninger , Judy Kauerauf , Janet Hamilton , Kaiser Permanente , Centers For Disease , Us Centers For Medicare Medicaid Services , Henryj Kaiser Family Foundation , Drug Administration , Illinois Department Of Public Health , Tribune Content Agency , Nevada State Public Health Laboratory , Columbia University Brown Institute For Media Innovation , Clinical Laboratory Improvement Amendments ,