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DBT-NIBMG creates world's first database of genomic variants of oral cancer – India Education | Latest Education News | Global Educational News

Jul 8, 2021
dbGENVOC is a browsable online database of GENomic Variants of Oral Cancer and is a free resource. First release of dbGENVOC contains (i) ~24 million somatic and germline variants derived from whole exome sequences of 100 Indian oral cancer patients and whole genome sequences of 5 oral cancer patients from India, (ii) somatic variation data from 220 patient samples drawn from the USA and analyzed by TCGA-HNSCC project and (iii) manually curated variation data of 118 patients from recently published peer-reviewed publications. Variants were identified by the community approved best practice protocol and annotated using multiple analytic pipeline.
dbGENVOC is not just a catalogue of genomic variants, it has a built-in powerful search engine. It also allows a reasonable extent of statistical and bioinformatic analysis to be carried out online, including identifying variants in associated altered pathways in oral cancer. ....

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It's guard up again with new UK Covid strain- The New Indian Express

Express News Service
BENGALURU: The new SARS-CoV-2 virus variant discovered in the United Kingdom and which has slipped into India has people worried in Karnataka. That is understandable as ten Covid-19-positive patients have been detected in Karnataka, the highest in the country. Of these, six are in Bengaluru (three in Bommanahalli, two in Rajajinagar and one in JP Nagar), while four are in Shivamogga.
The UK variant also referred to as “SARS-CoV-2 VOC 202012/01” (the first ‘Variant Of Concern’ from 2020 December), or “B.1.1.7” was identified early December by UK health officials through genome sequencing of two samples collected on September 20. The tests, confirming the new variant, estimated it to have up to 70 per cent higher transmissibility than its original version. ....

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Centre identifies 10 regional laboratories for genome sequencing to detect new COVID variant

Centre identifies 10 regional laboratories for genome sequencing to detect new COVID variant
The emergence of the new coronavirus strain in the UK has required India to increase viral genomic surveillance in order to understand the spread of the virus in a rapid and robust manner.
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By PTI
NEW DELHI:
Ten regional laboratories have been identified by the Centre where states will send five per cent of their COVID-19 positive samples for genome sequencing to detect the new coronavirus variant that has emerged in the United Kingdom recently.
The health ministry has also established the Indian SARS-CoV-2 Genomics Consortium (INSACOG) for laboratory and epidemiological surveillance and expand whole genome sequencing of the coronavirus in the country, aiding in the understanding of how the virus spreads and evolves. ....

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10 regional laboratories identified for genome sequencing to detect new coronavirus variant | India News

NEW DELHI: Ten regional laboratories have been identified by the Centre where states will send five per cent of their Covid-19 positive samples for genome sequencing to detect the new coronavirus variant that has emerged in the United Kingdom recently.
The health ministry has also established the Indian SARS-CoV-2 Genomics Consortium (INSACOG) for laboratory and epidemiological surveillance and expand whole genome sequencing of the coronavirus in the country, aiding in the understanding of how the virus spreads and evolves.
The emergence of the new coronavirus strain in the UK has required India to increase viral genomic surveillance in order to understand the spread of the virus in a rapid and robust manner. ....

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New UK strain threat: India to begin genome sequencing of genes of 5% Covid +ve samples

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New UK strain threat: India to begin genome sequencing of genes of 5% Covid +ve samples
The National Task Force on Covid-19 has recommended that as part of âprospective surveillanceâ, 5% of positive cases from all states and UTs be tested for whole-genome sequencing to check for the presence of the âUK strainâ that is seen to have a higher degree of infectiousness.
The moves come weeks after the UK found a variant with an unusually high number of changes, including some that are believed to make the virus 56%-70% more transmissible. The new strain is yet not known to cause more severe disease or make the current class of vaccines ineffective. ....

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