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Could procalcitonin indicate bacterial co-infections in COVID-19 patients?

Could procalcitonin indicate bacterial co-infections in COVID-19 patients?
medRxiv preprint server.
Background
Since its emergence in December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of COVID-19, has already infected more than 92 million people and claimed about 2 million lives globally. Alike other respiratory infections, the presence of microbial co-infection can increase the disease severity and mortality in critically ill COVID-19 patients. To prevent adverse outcomes of microbial co-infection, empiric antibiotics are frequently used as a part of the standard of care treatment for in-hospital COVID-19 patients. However, several clinical studies have shown that the risk of bacterial co-infection in COVID-19 patients is lower compared to other viral infections. ....

Sanchari Sinha Dutta , Austin Health , Antimicrobial Stewardship Tool , Disease Severity , Aagenaes Syndrome , Antimicrobial Resistance , Sars Cov 2 , Corona Virus , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , சஞ்சரி சீன்ஹா தத்தா , ஆஸ்டின் ஆரோக்கியம் , ஆண்டிமைக்ரோபியல் பணிப்பெண் கருவி , நோய் தீவிரம் , ஆண்டிமைக்ரோபியல் எதிர்ப்பு , கொரோனா வைரஸ் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,

New DNA test quickly identifies secondary infections in COVID-19 patients

Researchers have developed a DNA test to quickly identify secondary infections in COVID-19 patients, who have double the risk of developing pneumonia while on ventilation than non-COVID-19 patients. ....

United Kingdom , Andrew Conway Morris , Mailis Maes , Gordon Dougan , Vilas Navapurkar , Martin Curran , Emily Henderson , University Of Cambridge , Public Health England Cambridge , Public Health England , Study Co , Cambridge University Hospitals , Department Of Medicine , Professor Gordon Dougan , Study Co Author , Intensive Care Consultant , Anti Inflammatory , Intensive Care , Public Health , ஒன்றுபட்டது கிஂக்டம் , ஆண்ட்ரூ கான்வே மோரிஸ் , கோர்டந் டௌகந் , மார்டின் குர்ரன் , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் கேம்பிரிட்ஜ் , பொது ஆரோக்கியம் இங்கிலாந்து கேம்பிரிட்ஜ் ,

Scientists make new discovery in the quest for novel antibiotics

Scientists make new discovery in the quest for novel antibiotics
Scientists who highlighted the bug-busting properties of bacteria in Northern Irish soil have made another exciting discovery in the quest to discover new antibiotics.
The Traditional Medicine Group, an international collaboration of scientists from Swansea University, Brazil and Northern Ireland, have discovered more antibiotic-producing species and believe they may even have identified new varieties of antibiotics with potentially life-saving consequences.
Antibiotic resistant superbugs could kill up to 1.3 million people in Europe by 2050 - the World Health Organisation (WHO) describes the problem as one of the biggest threats to global health, food security, and development today . ....

United States , Simms Adu , Paul Facey , Hamid Bakshi , Gerry Quinn , Emily Henderson , Swansea University Nada Alharbi , Traditional Medicine Group , Swansea University , Ulster University , World Health Organisation , Northern Irish , Northern Ireland , West Fermanagh , County Fermanagh , Study Lead Researchers , Nada Alharbi , ஒன்றுபட்டது மாநிலங்களில் , பால் முகம் , ஹமிட் பக்ஷி , ஜெர்ரி க்வின் , எமிலி ஹென்டர்சன் , பாரம்பரிய மருந்து குழு , ஸ்வான்சீ பல்கலைக்கழகம் , அல்ஸ்டர் பல்கலைக்கழகம் , உலகம் ஆரோக்கியம் ஆர்கநைஸேஶந் ,

Imaging Method reveals whether Antibiotics reach Bacteria hiding in Tissues

Jan 15 2021 Read 411 Times
During bacterial infections such as tuberculosis, bacteria enter human cells posing a challenge for treatment, as antibiotics must reach and enter all infected cells in order to be effective. If researchers could select for or develop more effective antibiotics based on where they reach, this may reduce the length of treatment needed, which in turn could reduce the risk of antibiotic resistance developing.
Scientists at the Francis Crick Institute and the University of Western Australia have developed a new imaging method to see where in the infected tissues and in the cells, an antibiotic given to treat tuberculosis had reached the bacteria. The scientists are continuing to work on the method, adapting it for other types of antibiotic and to image multiple antibiotics at the same time. ....

Tony Fearns , Max Gutierrez , Pathogen Interactions In Tuberculosis Laboratory , Francis Crick Institute , University Of Western Australia , Western Australia , Host Pathogen Interactions , Tuberculosis Laboratory , டோனி பயம் , அதிகபட்சம் குட்டரெஸ் , நோய்க்கிருமி இடைவினைகள் இல் காசநோய் ஆய்வகம் , பிரான்சிஸ் கிரிக் நிறுவனம் , பல்கலைக்கழகம் ஆஃப் மேற்கு ஆஸ்திரேலியா , மேற்கு ஆஸ்திரேலியா , தொகுப்பாளர் நோய்க்கிருமி இடைவினைகள் , காசநோய் ஆய்வகம் , நுண்ணுயிர் எதிர்ப்பிகள் , நோய்த்தொற்றுக்கு உள்ளானவர் ,

Phage therapy offers hope in fight against antibiotic resistance and superbugs

Phage therapy offers hope in fight against antibiotic resistance and superbugs
Posted
ThuThursday 14
updated
TueTuesday 19
JanJanuary 2021 at 4:09am
Scientists Ali Khalid and Ruby Lin collect samples from the sewage system at a nursing home.
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Fishing for samples from a raw sewage pond isn t terribly pleasant work, but Ruby Lin hopes what she collects here will help avert a medical catastrophe.
Key points:
Phage therapy involves the use of specific viruses to target bacterial infections
Some doctors hope it will play a major role in stopping deaths caused by antibiotic-resistant bacteria
There have been promising results in clinical trials in Sydney, but the therapy has its drawbacks ....

New South Wales , United States , San Diego , Jon Iredell , Jeremy Barr , Frances Caratozzolo , Peter Collignon , Ruby Lin , Tom Patterson , Australian Commission On Safety , Organisation For Economic , Westmead Institute For Medical Research , Economic Cooperation , Australian Commission , Westmead Institute , Medical Research , Westmead Hospital , Professor Barr , புதியது தெற்கு வேல்ஸ் , ஒன்றுபட்டது மாநிலங்களில் , சான் டியாகோ , ஜான் இரேதெல்ள் , ஜெர்மி பார் , பீட்டர் சொல்லிக்கினோன் , ரூபி லின் , டோம் பேட்டர்சன் ,