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Flipping a Molecular Switch for Heart Fibrosis

Flipping a Molecular Switch for Heart Fibrosis
prnewswire.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from prnewswire.com Daily Mail and Mail on Sunday newspapers.

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Molecular analysis identifies key differences in lungs of cystic fibrosis patients

Nature Medicine
Healthy airways (left) show well-defined layers of ciliated cells (green) and basal stem cells (red). In airways affected by cystic fibrosis (right), the layers are disrupted, and scientists identified a transitioning cell type that combines properties of both stem cells and ciliated cells (red and green in the same cell).
A team of researchers from UCLA, Cedars-Sinai and the Cystic Fibrosis Foundation has developed a first-of-its-kind molecular catalog of cells in healthy lungs and the lungs of people with cystic fibrosis.
The catalog, described today in the journal Nature Medicine, reveals new subtypes of cells and illustrates how the disease changes the cellular makeup of the airways. The findings could help scientists in their search for specific cell types that represent prime targets for genetic and cell therapies for cystic fibrosis. ....

Brigitte Gomperts , Barry Stripp , Kathrin Plath , John Jed Mahoney , Gianni Carraro , Justin Langerman , National Cancer Institute , Cystic Fibrosis Foundation , Tumor Cell Biology Training Program , Sinai Board Of Governors Regenerative Medicine Institute , Parkerb Francis Foundation Fellowship , National Heart , Blood Institute , Edythe Broad Center , Stem Cell Research , Cystic Fibrosis Foundation Therapeutics Lab , Broad Stem Cell Research Center , National Institutes Of Health , David Geffen School Of Medicine , Wm Keck Foundation , Disease Research Program , Cystic Fibrosis Foundation Epithelial Stem Cell Consortium , Howard Hughes Medical Institute , Nature Medicine , Regenerative Medicine , Cystic Fibrosis Foundation Therapeutics ,

FDA Weighs Ban on Menthol Cigarettes, Which Disproportionately Addict — and Kill — Black Americans

FDA Weighs Ban on Menthol Cigarettes, Which Disproportionately Addict — and Kill — Black Americans
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FDA weighs ban on menthol cigarettes, which disproportionately addict — and kill — Black Americans

FDA weighs ban on menthol cigarettes, which disproportionately addict — and kill — Black Americans
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FDA weighs ban on menthol cigarettes, which disproportionately addict - and kill

FDA weighs ban on menthol cigarettes, which disproportionately addict - and kill - black Americans
By The Washington Post
Laura Reiley
Theo Wilson avoided smoking most of his adult life. He remembered the smell of menthol from his childhood, the smell of his father s cigarettes, his aunt s and his grandmother s. The minty smell of the cigarettes whose secondhand smoke gave him childhood asthma, the smell of the cigarettes that cut his grandmother s life short.
But in 2018, when he portrayed an Iraq War veteran in a play in Denver, his character was expected to smoke a marijuana cigarette onstage. The prop master got him an e-cigarette with a blinking blue light at the end, wrapping it in rolling paper to look convincing. After everything he knew, after railing against smoking, he got hooked. Over-the-counter minty e-cigarettes became fat vape pens, vaping turned into menthol and clove tobacco cigarettes. He bummed Kools and Newports - two of the most popular mentho ....

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