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NIH awards $3.1 million grant for Washington University, St. Jude ALS research Five-year grant to McKelvey School of Engineering’s Pappu and co-PI Mittag will support study of RNA-binding proteins March 5, 2021 SHARE Rohit Pappu, the Edwin H. Murty Professor of Engineering in the Department of Biomedical Engineering, received funds to study RNA-binding proteins that are mutated in patients with familial forms of amyotrophic lateral sclerosis (ALS). Scientists from Washington University in St. Louis and St. Jude Children’s Research Hospital have been awarded a five-year $3.1 million grant from the National Institute of Neurological Disorders and Stroke, an affiliate of the National Institutes of Health (NIH). ....
Rohit Pappu, the Edwin H. Murty Professor of Engineering in the Department of Biomedical Engineering, received funds to study RNA-binding proteins that are mutated in patients with familial forms of amyotrophic lateral sclerosis (ALS). Scientists from Washington University in St. Louis and St. Jude Children’s Research Hospital have been awarded a five-year $3.1 million grant from the National Institute of Neurological Disorders and Stroke, an affiliate of the National Institutes of Health (NIH). Rohit Pappu, the Edwin H. Murty Professor of Engineering in the Department of Biomedical Engineering in the McKelvey School of Engineering at Washington University, and Tanja Mittag, of the St. Jude Department of Structural Biology, received the funds to study RNA-binding proteins that are mutated in patients with familial forms of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. ....
As any cook knows, some liquids mix well with each other, but others do not. For example, when a tablespoon of vinegar is poured into water, a brief stir suffices to thoroughly combine the two liquids. ....
Loading video. VIDEO: : Researchers in the laboratories of Princeton University scientists Joshua Shaevitz, Howard Stone, and Sabine Petry have discovered that surface tension drives the liquid-like protein TPX2 to form globules that. view more Credit: Video by the authors: Sagar U. Setru, Bernardo Gouveia, Raymundo Alfaro-Aco, Joshua W. Shaevitz, Howard A. Stone and Sabine Petry As any cook knows, some liquids mix well with each other, but others do not. For example, when a tablespoon of vinegar is poured into water, a brief stir suffices to thoroughly combine the two liquids. However, a tablespoon of oil poured into water will coalesce into droplets that no amount of stirring can dissolve. The physics that governs the mixing of liquids is not limited to mixing bowls; it also affects the behavior of things inside cells. It s been known for several years that some proteins behave like liquids, and that some liquid-like proteins don t mix together. However, ....