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10 Puzzling Unsolved Mysteries From The History Of China

10 Puzzling Unsolved Mysteries From The History Of China
listverse.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from listverse.com Daily Mail and Mail on Sunday newspapers.

Liu Cheng , Hong Kong , United Kingdom , United States , Chu Anping , Yellow Sea , Oceans General , Emperor Jianwen , Zhang Chai , Emperor Yongle , Zhu Changluo , Noda Tsuyoshi , Song Jiaoren , Mukai Toshiaki , Kawashima Yoshiko , Hong Kongers , Utagawa Kuniyoshi , Emperor Wanli , Nichi Shimbun , Jamie Frater , Emperor Qin , Xu Fu , Lam Bun , Deng Xiaoping , Sun Yat Sen , Aisin Gioro Xianyu ,

P2X7R in Mast Cells is a Potential Target for Salicylic Acid and Aspir


7 P2X receptors carry out many important functions in the central and peripheral nervous system.
8,9 Compelling evidence has shown that P2X3, P2X4 and P2X7 receptors are involved in the pathogenesis of chronic pain.
10 P2X7R exists in neurons and glial cells of the nervous system, but is mainly expressed in cells of immune origin such as monocytes, macrophages, and microglia.
11 The absence of P2X7R can completely eliminate the inflammatory and neuropathic hypersensitivity to both mechanical and temperature stimulation.
12–14 P2X7R in microglia plays an important role in chronic neuropathy and inflammatory pain by releasing pro-inflammatory cytokines such as IL-1β. ....

United States , Johns Hopkins , Tocris Bioscience , Research Collaboratory , Shanghai Institute Of Biochemistry , China Pharmaceutical University , Dong Lab , Protein Data Bank , Molecular Devices Inc , Committee Of Nanjing University Chinese Medicine , A Molecular Devices Inc , Animal Care , Use Committee , Nanjing University , Chinese Medicine , Alomone Labs , Vazyme Biotech , Taq Mastermix , Master Mix , Assay Kit , Yuanye Biotech , Rabbit Anti P , Mouse Peritoneal Mast Cell , Shanghai Institute , Genscript Biotech , Cell Current Clamp Recordings ,

LncRNA AFAP1-AS1 Modulates Gastric Cancer Cell Proliferation


13 and hepatocellular carcinoma.
14,15 In a previous analysis of the lncRNA expression profile using a microarray assay, we found that AFAP1-AS1 was upregulated in six GC tissues compared with paired non-cancerous tissues. To investigate the relationship between AFAP1-AS1 and GC, the expression of AFAP1-AS1 was further verified in a study involving a larger sample size composed of tissues and six different GC cell lines. In addition, the potential functions of AFAP1-AS1 on the proliferation, migration, and invasion of GC cells was also investigated in this study.
Materials and Methods
Tissue Samples and RNA Extraction
In this investigation, 97 fresh frozen GC and their paired non-cancerous tissues were collected at Fuzhou General Hospital, which were used to assess the expression of AFAP1-AS1. The collection and preservation of fresh GC tissue samples were carried out as previously described. ....

Eteläuomen Läi , United States , Trizol Invitrogen , Shanghai Institute Of Biochemistry , Cancer Institute , Cell Bank , Chinese Academy Of Sciences , Mix Red Ribobio Co Ltd , Ethics Committee , Fuzhou General Hospital , Joint Logistics Team Hospital , Expression Profile , Kangchen Biotech , Beijing Cancer Institute , Shanghai Institute , Cell Biology , Chinese Academy , Time Quantitative Polymerase Chain Reaction , Mix Kit , Primer Sequences , Cell Counting , Molecular Devices , Cell Light Edu , Proliferation Kit , Apollo Dye , Blotting Assay ,

NIMH » Section on Molecular Neuroscience Staff


Section on Molecular Neuroscience Staff
Lee E. Eiden is the Chief of the Section on Molecular Neuroscience in the National Institute of Mental Health Intramural Research Program of the National Institutes of Health, Bethesda, Maryland. He received his B.A. in Chemistry from Northwestern University in Evanston Illinois, and Ph.D. in Pharmacology from The University of Kansas, and was a Staff Fellow, PRAT Fellow, and Senior Staff Fellow in the NIMH Intramural Research Program before joining the faculty as a Principal Investigator and Chief of the Unit on Cell Biology in 1987, and Chief of the Section on Molecular Neuroscience in 1992. His work at the NIH has focused on stimulus-secretion-synthesis coupling, characterization of the vesicular and secretory proteins mediating chemically coded neurotransmission, including chromogranin A, VMAT1, VMAT2, and VAChT and signaling pathways underlying neuropeptide-mediated stress responses. More recently, the laboratory has been involved i ....

New York , United States , Johns Hopkins University , National Institutes Of Health , Baylor College Of Medicine , Abraham Worcel , Paul Feinstein , Cleversys Homecagemonitor , Clark Lindgren , Ted Abel , Husseini Manji , Zhihong Jiang , Sam Dahlke , Tabinda Salman , Wenqin Xu , Wenqin Wen Xu , Lawrence Kedes , Snehajyoti Chatterjee , Tomris Mustafa , Haiying Zhang , Dana Bakalar , Lee Eiden , Maribeth Eiden , Phil Ziegler , Harris Busch , Earl Thomas ,