Novosteo, Inc. s NOV004 has shown promise in live animals in the acceleration of fracture healing when delivered systemically. The compound is unique in that it concentrates at the fracture site while avoiding accumulation in the rest of the body. Proceeds from the financing will be used to advance NOV004 into clinical development that will begin in the first half of 2021. Bone injuries and disease are one of the most challenging health issues facing all ages, especially for the elderly. Despite the advent of preventive measures, one in three hip fracture patients who are 65 and older will die within a year; many deaths occur as a result of the complications due to slow fracture healing and long-term immobilization.
Research Bridge Partners' Portfolio Company, Novosteo, Inc., Closes $5.5 Million in Series A Financing prnewswire.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from prnewswire.com Daily Mail and Mail on Sunday newspapers.
E-Mail IMAGE: The image shows fractured femurs at three weeks post-fracture. Yellow and orange colors indicate higher density bone than purple and blue and the green arrows point towards the fracture site.. view more Credit: Novosteo Inc. Novosteo Inc., a preclinical-stage biotechnology startup focused on the development of bone-targeted therapeutics, announced Thursday (February 4) the closing of a $5.5 million in Series A financing to advance its development of the first-ever targeted bone anabolic agent NOV004. The compound has shown promise in live animals in the acceleration of fracture healing when delivered systemically. NOV004 is unique in that it concentrates at the fracture site while avoiding accumulation in the rest of the body. Proceeds from the financing will be used to advance NOV004 into clinical development that will begin in the first half of 2021.
Date Time Share Bone treatment startup raises $5.5 M in Series A financing, names pharmaceutical leader William Boyle as CEO The image above shows fractured femurs at three weeks post-fracture. Yellow and orange colors indicate higher density bone than purple and blue and the green arrows point towards the fracture site. The “targeted” bone received Novosteo’s injectable-targeted drug, whereas the control bone did not receive drug, representing current therapies. Comparing the two bones, the additional bone growth caused by Novosteo’s drug could help people with fractures return to normal activity quickly in the future. (Image provided by Novosteo Inc.)
How to preserve an abundance of stone fruit Richard Cornish Photo: iStock I have so much stone fruit – how do I preserve it? L. Handley When I was growing up on the farm, my family inherited an orchard of gnarled fruit trees. Their limbs were cloaked in layers of lichen and riddled with various forms of canker. They had grown protected from the prevailing winds by a hedgerow of cypress. Every odd year they threw a surfeit of fruit. This was in the era before freezers, so some of the softer fruit were turned into jams. We cooked apricots with an equal weight of sugar plus the fleshy kernel of the apricot pip to add a marzipan note to the conserve, plus half lemons to add acid and pectin. Apricots love a touch of warm spice such as cinnamon or cardamom and even a pinch of salt.